John Charles O'Donnell, BA, MS, PhD

faculty photo
Research Assistant Professor of Neurosurgery
Department: Neurosurgery
Graduate Group Affiliations

Contact information
3900 Woodland Ave
Philadelphia, PA 19104
BA (Biology, Philosophy Minor)
LaSalle University, 2004.
MS (Biology)
Towson University, 2009.
PhD (Neuropharmacology)
University of Pennsylvania, 2016.
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Description of Research Expertise

Traumatic Brain Injury; Disorders of Consciousness; Neurotrauma Rehabilitation and Recovery; Neuroregenerative Medicine; Neurotherapeutics Development; Tissue Engineering to Facilitate Repair, Regeneration, and Recovery after Neurotrauma and Neurodegeneration; Astrocytes; Mitochondria; Biomedical Translation/Commercialization

Selected Publications

Daniel J. Han1, Kevin D. Browne, Kathryn L. Wofford, Dmitriy Petrov, D. Kacy Cullen, John C. O’Donnell: The Effects of Rotational Acceleration Traumatic Brain Injury on Intracranial Hypertension and Astrocytic Proteins Associated with Cerebral Edema. National Neurotrauma Society June 2024.

Purvis EM, Garcia-Epelboim AD, Krizman EN, O'Donnell JC*, Cullen DK* (*CO-SENIOR) : A three-dimensional tissue-engineered rostral migratory stream as an in vitro platform for subventricular zone-derived cell migration Frontiers in Bioengineering and Biotechnology June 2024.

Dimple Chouhan, Wisberty J Gordián Vélez, Laura A Struzyna, Dayo Adewole, Erin R Cullen, Justin C Burrell, John C O'Donnell, D Kacy Cullen: Generation of contractile forces by three-dimensional bundled axonal tracts in micro-tissue engineered neural networks. Frontiers in Molecular Neuroscience March 2024.

O’Donnell JC: Disorders of nomenclature. CNS Neuroscience & Therapeutics January 2024.

O’Donnell JC, Petrov D.: Porcine Models of Neurotrauma and Neurological Disorders. Biomedicines January 2024.

Krizman E, Purvis EM, Garcia-Epelboim AD, O’Donnell JC, Cullen DK: A tissue-engineered rostral migratory stream as an in vitro platform to investigate subventricular zone-derived neuroblast migration. Society for Neuroscience November 2023.

Daniel Han, Kevin D. Browne, Natalia Fedorczak, Michael R. Grovola, Elizabeth Krizman, Dmitriy Petrov, D. Kacy Cullen, John C. O’Donnell: Astrocytic changes after closed-head, rotational acceleration TBI in swine. Society for Neuroscience November 2023.

Erin M. Purvis, Andrés D. Garcia-Epelboim, John C. O’Donnell*, D. Kacy Cullen*: Development and characterization of an in vitro platform to investigate subventricular zone-derived neuroblast migration along a tissue-engineered rostral migratory stream. IBRO World Congress of Neuroscience 2023 Meeting in Granada, Spain September 2023.

Erin M Purvis, Natalia Fedorczak, Annette Prah, Daniel Han, John C O’Donnell: Porcine Astrocytes and Their Relevance for Translational Neurotrauma Research. Biomedicines 11(9), August 2023.

Connor A Wathen, Yohannes G Ghenbot, Ali K Ozturk, D Kacy Cullen, John C O’Donnell, Dmitriy Petrov: Porcine Models of Spinal Cord Injury. Biomedicines 11(8), August 2023.

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Last updated: 06/30/2024
The Trustees of the University of Pennsylvania