Faculty

Katheryn Alexandra Quilico Cousins-Gershenson, PhD

Research Assistant Professor of Neurology

Department: Neurology

Graduate Group Affiliations

Neuroscience

Contact information

Richards Medical Building, Suite 600B
3700 Hamilton Walk
Philadelphia, PA 19104

Email:
katheryn.cousins@pennmedicine.upenn.edu

Education:
BA ( Biological Sciences)
University of Chicago, 2007.
PhD (Neuroscience)
Brandeis University, 2015.

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Description of Research Expertise

Biofluid markers of neuropathology

Selected Publications

Brown CA, Mundada NS, Cousins KAQ, Sadeghpour N, Lyu X, McGrew E, Korecka M, Chen-Plotkin A, Xie L, Wisse LEM, Detre JA, McMillan CT, Lee EB, Nasrallah IM, Das SR, Mechanic-Hamilton D, Yushkevich PA, Shaw LM, Wolk DA; Alzheimer’s Disease Neuroimaging Initiative.: Evaluation of Copathology and Clinical Trajectories in Individuals With Tau-Clinical Mismatch. JAMA Neurol 83: 126-136, Feb 2026.

Cousins KAQ, Boyle R, Morse C, Verma A, Brown CA, O'Brien KS, Serper M, Dehghani N; Penn Medicine BioBank; McMillan CT, Lee EB, Shaw LM, Wolk DA.: Electronic Health Records to Test Multimorbidity Influences to Plasma Biomarker Interpretation for Alzheimer's Disease. Ann Neurol Dec 2025.

Kwiecinski, Dratch, Andrews, Dengel, Kamel, Legaspi, McMillan, Massimo, Cousins, & Irwin : Evaluating the Impact of Predictive Genetic Counseling in Frontotemporal Dementia: A Pilot Analysis. National Society of Genetic Counselors (NSGC) 44th Annual Conference Nov 2025.

Ohm, Capp, Sabitini, Cousins, Phillips, Rascovsky, Wolk, Lee, McMillan, & Irwin : Selectively vulnerable myeloarchitecture in behavioral variant frontotemporal dementia. Society for Neuroscience (SfN) Nov 2025.

Luna, Cousins, Emrani, Luk, Lee, Lee, Weintraub, Xie, Chen-Plotkin, Bennett, & Irwin: Lewy Pathology correlates with neuroinflammation in the hippocampus of Synucleinopathy patients in a subregion specific manner. International Congress of Parkinson’s Disease and Movement Disorders Oct 2025.

Brown CA, Cousins KAQ, Korecka M, McGrew E, Chen-Plotkin A, Detre JA, McMillan CT, Lee EB, Das SR, Mechanic-Hamilton D, Yushkevich PA, Nasrallah IM, Shaw LM; Alzheimer’s Disease Neuroimaging Initiative; Wolk DA.: Temporal Modeling of Amyloid and Tau Trajectories in Alzheimer's Disease using PET and Plasma Biomarkers. medRxiv Sep 2025.

Wadhwani, Goldberg, Cousins, Brown, Dehghani, Sreepada, Fu, De Jager, Bennett, Wolk, Lee, White III, Walker, Richardson, PART Working Group, Alzheimer’s Disease Neuroimaging Initiative, Farrell, Crary, Zhou, & McMillan : Aging Against the Clock: Epigenetic Signatures of Regional Tau Pathology and Cognitive Decline. American Neurological Association (ANA) Sept 2025.

Arezoumandan, Emrani, Teunissen, Capp, Ohm, Cousins, Phillips, McMillan, Robinson, Mechanic-Hamilton, Lee, Yushkevich, Das, Wolk, & Irwin : NFT maturation and tau mediated neurodegeneration in Alzheimer’s disease with concomitant LATE-NC. American Neurological Association (ANA) Sept 2025.

Boyle R, Dehghani N, Emrani S, Wadhwani AR, Matyi M, Cousins KAQ, Rhodes E, Nelson B, Stites SD, Xie SX, Dratch L, Van Deerlin VM, Snyder A, Irwin DJ, McMillan CT, Massimo L.: Higher neighborhood deprivation is associated with accelerated disease progression in behavioral-variant frontotemporal degeneration. Alzheimers Dement Behav Socioecon Aging Sept 2025.

Cousins KAQ, Korecka M, Wan Y, Vulaj A, Brown C, Tropea TF, Lee EB, Tosun D, Landau SM, Okonkwo OC, Mindt MR, Weiner MW, Irwin DJ, Wolk DA, Shaw LM; and the Alzheimer's Disease Neuroimaging Initiative.: Comparison of plasma p-tau217/Aβ42, p-tau217, and Aβ42/Aβ40 biomarkers by race to detect Alzheimer's disease. Alzheimers Dement Aug 2025.