Faculty

Joseph Cichon, MD PhD

Assistant Professor of Anesthesiology and Critical Care

Department: Anesthesiology and Critical Care

Graduate Group Affiliations

Neuroscience

Contact information

Hospital of the University of Pennsylvania
Department of Anesthesiology and Critical Care
3400 Spruce Street, Suite 680 Dulles
Philadelphia, PA 19104

Education:
BS
Pennsylvania State University, 2008.
MS
Pennsylvania State University, 2009.
PhD (Neuroscience & Physiology)
NYU School of Medicine, 2015.
MD
NYU School of Medicine, 2017.

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Description of Research Expertise

The cellular and circuit mechanisms of rapid-acting antidepressants.

Selected Publications

Joseph Cichon, Renyu Liu, and Hoang V. Le: Therapeutic Potential of Salvinorin A and Its Analogues in Various Neurological Disorders. Transl Perioper Pain Med 9(2): 452–457, June 2022.

Ingrid Fadelli : Study shows that ketamine switches neuronal activity in the neocortex. Medical Xpress 12 2022.

Joseph Cichon, Andrzej Z. Wasilczuk, Loren L. Looger, Diego Contreras, Max B. Kelz & Alex Proekt: Ketamine triggers a switch in excitatory neuronal activity across neocortex. Nature Neuroscience Nature Neuroscience 2022.

Sun L, Zhou H, Cichon J, Yang G.: Experience and sleep-dependent synaptic plasticity: from structure to activity. Philos Trans R Soc Lond B Biol Sci 375: 20190234, May 2020.

Cichon J, Wasilczuk A, Looger L, Kelz M, Proekt : Ketamine dissociation triggers a universal switch in neuronal activity across neocortex. Pennsylvania Anesthesiology Resident Research Conference (PARRC), Virtual May 2020 Notes: Poster Presentation.

Cichon J, Magrané J, Shtridler E, Chen C, Sun L, Yang G, Gan WB.: Imaging neuronal activity in the central and peripheral nervous systems using new Thy1.2-GCaMP6 transgenic mouse lines. J Neurosci Methods 334: 108535, Jan 2020.

Cichon J, Wasilczuk A, Yang G, Kelz M: Ketamine dissociation triggers a universal switch in neuronal activity across neocortex. Pennsylvania Anesthesiology Resident Research Conference (PARRC), Pittsburgh, PA May 2019 Notes: Poster Presentation.

Alder A, Zhao R, Shin M, Yasuda R, Gan W: Somatostatin-expressing interneurons enable and maintain learning-dependent sequential activation of pyramidal neurons. Neuron 102(1): 202-217, Feb 2019 Notes: Developed the motor learning paradigm used in this paper. Made the original discovery that the activity of somatostatin neurons is differentially modified by different tasks.

Cichon J, Sun L, Yang G.: Spared Nerve Injury Model of Neuropathic Pain in Mice. Bio Protoc 8: e2777, Mar 2018.

Cichon J, Blanck TJJ, Gan WB, Yang G.: Activation of cortical somatostatin interneurons prevents the development of neuropathic pain. Nat Neurosci 20: 1122-1132, Aug 2017.