Faculty

Ran Barzilay, MD, PhD

Assistant Professor of Psychiatry

Department: Psychiatry

Graduate Group Affiliations

Neuroscience

Contact information

10th Floor, Gates Building
Hospital of the University of Pennsylvania
3400 Spruce St.
Philadelphia, PA 19104

Office: 215-662-7559
Fax: 215-662-7903

Email:
ran.barzilay@pennmedicine.upenn.edu

Publications

Search PubMed for articles

Education:
BSc (Preclinical M.D. Studies)
Tel Aviv University, 2004.
PhD (Neuroscience)
Tel Aviv University, 2008.
MD
Tel Aviv University, 2011.

Links
Search PubMed for articles
Lifespan Brain Institute website
Personal lab website

Permanent link

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Description of Research Expertise

In BarziLab, we are interested in what drives variability in the development of brain and behavior in children and adolescents who develop under stress. We are especially interested in understanding mechanisms of risk and resilience leading to youth suicidal behavior. Using large datasets of youth who have been genotyped and deeply phenotyped, we study how a myriad of environmental exposures (such as trauma and poverty) dynamically interact amongst themselves (i.e., within the exposome), as well as with biological factors (genetic, epigenetic, immune) to drive suicidal behavior. We are committed to conduct impactful translational science that will help reduce teen suicide.

Selected Publications

Sha Z, Sun KY, Jung B, Barzilay R, Moore TM, Almasy L, Forsyth JK, Prem S, Gandal MJ, Seidlitz J, Glessner JT, Alexander-Bloch AF.: Copy Number Variant Architecture of Child Psychopathology and Cognitive Development in the ABCD Study. Am J Psychiatry 182: 763-778, Aug 2025.

Ered A, Dietterich TE, Shahriar SS, Wong TY, Moore TM, Ruparel K, Barzilay R, Taylor JH, Calkins ME, Gur RC, Gur RE.: Environmental Adversity Is Associated With Attenuated Positive Symptoms and Complex Cognition in a Long-term Follow-up of the Philadelphia Neurodevelopmental Cohort. Schizophr Bull 51: 871-882, Jul 2025.

White LK, Calkins ME, Himes MM, Moore TM, Gur RC, Barzilay R, Gur RE.: Delineating the Transmission of Subthreshold Psychosis Symptoms Across Generations: The Philadelphia Family Neurodevelopmental Cohort. Schizophr Bull 51: 906-915, Jul 2025.

Visoki E, Moore TM, Ruiz VM, Fein JA, Calkins ME, Gur RC, Benton TD, Gur RE, Tsui FR, Barzilay R.: Prediction of Adolescent Suicide Attempt by Integrating Clinical, Neurocognitive and Geocoded Neighborhood Environment Data. Schizophr Bull 51: 895-905, Jul 2025.

Calkins ME, Butler ER, Moore TM, Ered A, Taylor JH, White LK, Barzilay R, Ruparel K, Larsen B, Shahriar SS, Dietterich TE, Roalf DR, Wolf DH, Satterthwaite TD, Gur RC, Gur RE.: Longitudinal Trajectories of Clinical Features in Community Youth With Recurrent Psychosis Spectrum Symptoms: Findings From the Philadelphia Neurodevelopmental Cohort. Schizophr Bull 51: 858-870, Jul 2025.

Sun KY, Schmitt JE, Moore TM, Barzilay R, Almasy L, Schultz LM, Mackey AP, Kafadar E, Sha Z, Seidlitz J, Mallard TT, Cui Z, Li H, Fan Y, Fair DA, Satterthwaite TD, Keller AS, Alexander-Bloch A.: Polygenic Risk, Psychopathology, and Personalized Functional Brain Network Topography in Adolescence. JAMA Psychiatry Jun 2025.

Chaiyachati BH, Catalano JL, Schultz LM, Almasy L, Visoki E, Seidlitz J, Moore TM, Taylor JH, Calkins ME, Gur RE, Barzilay R.: Mediating Role of Trauma Connecting Psychiatric Family History and Adolescent Mental Health. Biol Psychiatry Glob Open Sci 5: 100525, May 2025.

Michel N, Tran KT, Visoki E, Gataviņš MM, Ly C, Barzilay R.: Mental Health, Minority Stressors and Resilience Factors Among Early Adolescent Immigrant Youth. J Am Acad Child Adolesc Psychiatry May 2025.

Waller R, Kornfield SL, White LK, Chaiyachati BH, Barzilay R, Njoroge W, Parish-Morris J, Duncan AF, Himes MM, Rodriguez Y, Seidlitz J, Riis V, Burris HH, Gur RE, Elovitz MA.: Correction to: Clinician-reported childbirth outcomes, patient-reported childbirth trauma, and risk for postpartum depression. Arch Womens Ment Health May 2025.

Cooper AM, Visoki E, Tran KT, Elbaz E, Gataviņš MM, McKetta S, Fein JA, Benton TD, Barzilay R.: Prevalence of Suicidal Ideation and Suicide Attempts by Race and Gender in Three Large U.S. Adolescent Cohorts. Am J Psychiatry May 2025.