Faculty

Akhilesh B. Reddy, MA MB BChir PhD FRCP

faculty photo
Associate Professor of Pharmacology
Department: Pharmacology

Contact information
10-125 Smilow Center for Translational Research
Philadelphia, PA 19104
Education:
BA (Medical Sciences Tripos)
University of Cambridge (Downing College), 1998.
PhD (Molecular Neurobiology)
MRC Laboratory of Molecular Biology, Cambridge, 2003.
MB BChir (MB/PhD Programme)
University of Cambridge, 2003.
Permanent link
 

Description of Research Expertise

Circadian clocks, Sleep, Metabolism, Neural circuits, Deep Learning

Selected Publications

O'Neill, J. S. and A. B. Reddy*: Circadian clocks in human red blood cells. Nature 469(7331): 498-503, 2011.

O'Neill, J. S., G. van Ooijen, L. E. Dixon, C. Troein, F. Corellou, F. Y. Bouget, A. B. Reddy* and A. J. Millar*: Circadian rhythms persist without transcription in a eukaryote. Nature 469(7331): 554-558, 2011.

Olmedo M, O'Neill JS, Edgar RS, Valekunja UK, Reddy AB, Merrow M.: Circadian regulation of olfaction and an evolutionarily conserved, nontranscriptional marker in Caenorhabditis elegans. Proc Natl Acad Sci U S A. 109(50): 20479-84, 2012.

Edgar RS, Green EW, Zhao Y, van Ooijen G, Olmedo M, Qin X, Xu Y, Pan M, Valekunja UK, Feeney KA, Maywood ES, Hastings MH, Baliga NS, Merrow M, Millar AJ, Johnson CH, Kyriacou CP, O’Neill JS, Reddy AB*.: Peroxiredoxins are conserved markers of circadian rhythms. Nature 485(7399): 459-64, 2012.

Rey G, Valekunja UK, Feeney KA, Wulund L, Milev NB, Stangherlin A, Ansel-Bollepalli L, Velagapudi V, O’Neill JS, Reddy AB*.: The pentose phosphate pathway regulates the circadian clock. Cell Metabolism 24(3): 462-73, 2016.

Edgar RS, Stangherlin A, Nagy AD, Nicoll MP, Efstathiou S, O'Neill JS, Reddy AB.: Cell autonomous regulation of herpes and influenza virus infection by the circadian clock. Proc Natl Acad Sci U S A. 113(36): 10085-90, 2016.

Sandipan Ray*, Utham K. Valekunja*, Alessandra Stangherlin, Steven A. Howell, Ambrosius P. Snijders, Gopinath Damodaran, Akhilesh B. Reddy: Circadian rhythms in the absence of the clock gene Bmal1. Science 367(6479): 800-806, 2020.

Ratnasekhar Ch, Guillaume Rey, Sandipan Ray, Pawan K. Jha, Paul C. Driscoll, Mariana Silva Dos Santos, Dania M. Malik, Radoslaw Lach, Aalim M. Weljie, James I. MacRae, Utham K. Valekunja, and Akhilesh B. Reddy: Rhythmic glucose metabolism regulates the redox circadian clockwork in human red blood cells Nature Communications 12(1), 2021.

back to top
Last updated: 06/10/2021
The Trustees of the University of Pennsylvania