Yanxiang Deng, PhD

faculty photo
Assistant Professor of Pathology and Laboratory Medicine
Department: Pathology and Laboratory Medicine

Contact information
422 Curie Boulevard, Stellar-Chance Laboratories 713A
Philadelphia, PA 19104
Rensselaer Polytechnic Institute, 2018.
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Selected Publications

Deng, Y.#*, Bai, Z.#*, Fan R.*: Microtechnologies for single-cell and spatial multi-omics. Nature Reviews Bioengineering Jun 2023.

Zhang, D.#, Deng, Y.#*, Kukanja P, Agirre E, Bartosovic M, Dong M, Ma C, Ma S, Su G, Bao S, Liu Y, Xiao Y, Rosoklija GB, Dwork AJ, Mann JJ, Leong KW, Boldrini M, Wang L, Haeussler M, Raphael BJ, Kluger Y, Castelo-Branco G*, Fan R.*: Spatially resolved epigenome-transcriptome co-profiling of mammalian tissues at the cellular level. Nature Mar 2023.

Wang, Y., Malik, S., Suh, H.W., Xiao, Y., Deng, Y., Fan, R., Huttner, A., Bindra, R.S., Singh, V., Saltzman, W.M. and Bahal, R.: Anti-seed PNAs targeting multiple oncomiRs for brain tumor therapy. Science Advances Feb 2023.

Liu, Y., DiStasio, M., Su, G., Asashima, H., Enninful, A., Qin, X., Deng, Y., Nam, J., Gao, F., Bordignon, P., Cassano, M., Tomayko, M., Xu, M., Halene, S., Craft, J., and Fan, R.: High-plex protein and whole transcriptome co-mapping at cellular resolution with spatial CITE-seq. Nature Biotechnology Feb 2023.

Deng, Y., Bartosovic, M., Ma, S., Zhang, D., Liu, Y., Qin, X., Su, G., Xu, M.L., Halene, S., Craft, J.E., Castelo-Branco, G. and Fan, R.: Spatial profiling of chromatin accessibility in mouse and human tissues. Nature 609: 375–383, Aug 2022.

Deng Y, Bartosovic M, Kukanja P, Zhang D, Liu Y, Su G, Enninful A, Bai Z, Castelo-Branco G, Fan R.: Spatial-CUT&Tag: spatially resolved chromatin modification profiling at the cellular level. Science 375: 681-686, Feb 2022.

Liu Y#, Yang M#, Deng Y#, Su G, Enninful A, Guo C, Tebaldi T, Zhang D, Kim D, Bai Z, Norris E, Pan A, Li J, Xiao Y, Halene S, Fan R.(# Co-first author): High-Spatial-Resolution Multi-Omics Sequencing via Deterministic Barcoding in Tissue. Cell 183(6): 1-17, Dec 2020.

Deng Y, Finck A, and Fan R.: Single-cell omics analyses enabled by microchip technologies. Annual Review of Biomedical Engineering 21: 365-393, Jun 2019.

Xin G, Zhu W, Deng Y, Chung AJ, De S and Lian J: Microfluidics-enabled orientation and microstructure control of macroscopic graphene fibres. Nature Nanotechnology 14: 168-175, Jan 2019 Notes: No issue number.

Kizer M#, Deng Y#, Kang G-Y, Paiyz M, Wang X, Chung AJ. (# Co-first author) (Featured as cover image) : Hydroporator: A hydrodynamic cell membrane perforator for high-throughput vector-free nanomaterial intracellular delivery and DNA origami biostability evaluation. Lab on a Chip 19(10): 1747-1754, Jan 2019.

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Last updated: 08/11/2023
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