Faculty

Edward F Kreider, MD, PhD

Assistant Professor of Medicine (Infectious Diseases)

Department: Medicine

Graduate Group Affiliations

Contact information

1 UCity, Room 4072
25 N 38th St
Philadelphia, PA 19104

Office: 2674148561

Education
MS (Chemistry)
University of Pennsylvania, 2010.
BS (Biochemistry)
University of Pennsylvania, 2010.
PhD (Cell and Molecular Biology)
Perelman School of Medicine at the University of Pennsylvania, 2016.
MD
Perelman School of Medicine at the University of Pennsylvania, 2018.

Permanent link

> Perelman School of Medicine > Faculty > Details

Selected Publications

Skelly AN, Gristick HB, Li H, Gavor E, Connell AJ, Kreider EF, Marchitto L, Hogarty MP, Newby ML, Allen JD, Liu W, West AP Jr, Ayyanathan K, Campion MS, Winters K, Gordon CG, Osbaldeston RA, Akeley MJ, Li Y, Singh A, Cruickshank K, Park Y, Zhao C, Li X, Amereh K, Itallie EV, Carey JW, Albertus A, DeLaitsch AT, Keeffe JR, Lituchy MG, Walsh AA, Morris DJ, Habib R, Bibollet-Ruche F, Mishra N, Avillion G, Koranda NS, Plante SJ, Martella CL, Lora J, Wang EJD, Lewis MG, Martin MA, Nussenzweig MC, Seaman MS, Irvine DJ, Wiehe KJ, Haynes BF, Wagh K, Korber BT, Andrabi R, Crispin M, Weissman D, Bjorkman PJ, Hahn BH, Shaw GM.: Consistent Induction of Broadly Neutralizing HIV Antibodies by a Novel Two-Step Mechanism Informs Immunogen Design. Science 18(392): 6804, June 2026.

Marchitto L, Wagh K, Roark RS, Coleon S, Li H, Skelly AN, Hogarty MP, Habib R, Ding W, Ayyanathan K, Liu W, Sheng Z, Guo Y, Bal J, Smith LM, Sutherland LL, Park Y, Connell AJ, Bibollet-Ruche F, Lewis E, Plante SJ, Akeley MJ, Lora J, Zhao C, Carey JW, Martella CL, Li Y, Campion MS, Lituchy MG, Osbaldeston RA, Gordon CG, Albertus A, Su J, Noguchi C, Tam YK, Barbosa C, Liang B, Amereh K, Li X, Walsh AA, Irvine DJ, Andrabi R, Edwards RJ, Kreider EF, Weissman D, Shapiro L, Kwong PD, Korber BT, Haynes BF, Saunders KO, Hahn BH, Shaw GM.: Enhanced B cell priming induces broadly neutralizing HIV-1 apex antibodies. Nature June 2026 Notes: doi: 10.1038/s41586-026-10838-4. Epub ahead of print.

Skelly AN, Fan C, Keeffe JR, Ökten AB, Gavor E, Newby ML, Allen JD, Kreider EF, Ding W, Osbaldeston RA, Park Y, Connell AJ, Lituchy MG, Bibollet-Ruche F, Radford KM, P West A Jr, Peña-Hernández MA, Cruickshank K, Liu W, Li Y, Albertus A, McWilliams B, Russell RM, Konrath KM, Torres JL, Yuan M, Gao H, Montefiori DC, Saag MS, Goepfert PA, Kulp DW, Ward AB, Wilson IA, Shaw GM, Andrabi R, Crispin M, Weissman D, Wilen CB, Bjorkman PJ, Hahn BH.: mRNA delivery of a class 1/4 SARS-CoV-2 neutralizing antibody protects against diverse sarbecoviruses in a lethal mouse challenge model. Proc Natl Acad Sci U S A 123(24), Jun 2026 Notes: doi: 10.1073/pnas.2536870123. Epub 2026 Jun 8.

Ökten AB, Filler RB, Kung JL, Fang Z, McWilliams BC, Muscat-Rivera JE, Kegel MS, Olivi Gomes IM, Mankowski MC, Skelly AN, Melamed JR, Nice TJ, Lee S, Baldridge MT, Smith TJ, Wobus CE, Eisenbarth SC, Williams A, Serebryannyy LA, Douek DC, Weissman D, Chen S, Kreider EF, Craft JE, Wilen CB. : IgA is necessary and sufficient to prevent norovirus infection in mice. Sci Transl Med. 18(855), Jun 2026 Notes: doi: 10.1126/scitranslmed.aeb4878. Epub 2026 Jun 24.

Corrigan AR, Ngiow SF, Statzu M, Albertus A, Pampena MB, Nordin JML, Carro SD, Harper J, Stammen RL, Wood J, Ni H, Su J, Hajialyani M, Shuvaev VV, Alcalde V, Ali MA, Hamilton JT, Ramalingam R, Wu VH, Paiardini M, Weissman D, Wherry EJ, Kreider EF, Betts MR.: In vivo reprogramming of cytotoxic effector CD8 T cells via fractalkine-conjugated mRNA-LNPs. Sci Immunol 11: eaec3436, May 2026.

Skelly AN, Gristick HB, Li H, Gavor E, Connell AJ, Kreider EF, Marchitto L, Hogarty MP, Newby ML, Allen JD, Liu W, West AP Jr, Ayyanathan K, Campion MS, Winters K, Gordon CG, Osbaldeston RA, Akeley MJ, Lewis E, Li Y, Singh A, Cruickshank K, Park Y, Zhao C, Li X, Amereh K, Van Itallie E, Carey JW, Albertus A, DeLaitsch AT, Keeffe JR, Lituchy MG, Walsh AA, Morris DJ, Habib R, Bibollet-Ruche F, Mishra N, Avillion G, Koranda NS, Plante SJ, Martella CL, Lora J, Wang EJD, Lewis MG, Martin MA, Nussenzweig MC, Seaman MS, Irvine DJ, Wiehe KJ, Haynes BF, Wagh K, Korber B, Andrabi R, Crispin M, Weissman D, Bjorkman PJ, Hahn BH, Shaw GM.: Induction of broadly neutralizing HIV antibodies by a two-step mechanism informs vaccine design. Science May 2026.

Ladines-Lim JB, Yang WT, Tebas P, O'Donnell J, Koenig H, Kreider E, Dyer K, Anwar M, Rodriguez E, Patel S, Rodino K, Glaser L, Richterman A.: Delayed diagnosis of disseminated Mycobacterium intracellulare subsp. chimaera infective endocarditis via cell-free metagenomic next-generation sequencing: a case report. ASM Case Rep 1: e00003-25, May 2025.

Kreider EF, Ortega-Burgos Y, Dumeng-Rodriguez J, Gesualdi J, O'Brien C, Bracy D, Johnson J, Bowman J, Metzger D, Dine CJ, Favor K, Jordan-Sciutto KL, Momplaisir F.: Early Engagement in HIV Research: Evaluation of the Penn CFAR Scholars Program Aimed at Increasing Diversity of the HIV/AIDS Workforce. J Acquir Immune Defic Syndr 94(25): S28-S35, Oct 2023.

Kreider EF, Bar KJ.: HIV-1 Reservoir Persistence and Decay: Implications for Cure Strategies. Curr HIV/AIDS Rep 19(3): 194-206, Jun 2022.

Bricault CA, Yusim K, Seaman MS, Yoon H, Theiler J, Giorgi EE, Wagh K, Theiler M, Hraber P, Macke JP, Kreider EF, Learn GH, Hahn BH, Scheid JF, Kovacs JM, Shields JL, Lavine CL, Ghantous F, Rist M, Bayne MG, Neubauer GH, McMahan K, Peng H, Chéneau C, Jones JJ, Zeng J, Ochsenbauer C, Nkolola JP, Stephenson KE, Chen B, Gnanakaran S, Bonsignori M, Williams LD, Haynes BF, Doria-Rose N, Mascola JR, Montefiori DC, Barouch DH, Korber B.: HIV-1 Neutralizing Antibody Signatures and Application to Epitope-Targeted Vaccine Design. Cell Host Microbe 26(2): 296, Aug 2019.