Faculty

David A. Hill, MD, PhD, FAAP, FAAAAI

Assistant Professor of Pediatrics (Allergy/Immunology )

Department: Pediatrics

Graduate Group Affiliations

Contact information

Children's Hospital of Philadelphia
Division of Allergy and Immunology
Department of Pediatrics
Abramson Pediatric Research Center, Room 1208B
3615 Civic Center Blvd.
Philadelphia, PA 19104

Office: 215-590-2549
Fax: 267-426-0363
Lab: 267-426-7777

Publications

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Education:
BS (Biological Sciences, with honors)
Carnegie Mellon University, Elizabeth Jones Lab, 2005.
PhD (Cell and Molecular Biology)
University of Pennsylvania Perelman School of Medicine, David Artis Lab, 2011.
MD (Medicine)
University of Pennsylvania Perelman School of Medicine, 2013.

Links
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Clinical Profile
Research Profile
Lab Website

Permanent link

> Perelman School of Medicine > Faculty > Details

Description of Clinical Expertise

Food allergy, eosinophilic esophagitis, obesity-associated asthma.

Description of Research Expertise

The Hill Lab studies the effects of obesity and metabolism on immune health and inflammatory diseases. We use the unique approach of leveraging clinical epidemiology to guide our mechanistic studies of the immune system in animal models and patient samples. Our goal is to translate our discoveries into the development of novel preventative, diagnostic, and therapeutic approaches for human disease.

Selected Publications

Gabryszewski SJ, Hill DA: Immunoregulatory Effects of the Ketogenic Diet in a Mouse Model of Eosinophilic Esophagitis. American Society for Parenteral and Enteral Nutrition (ASPN) Annual Meeting. Tampa, FL. Mar 2024 Notes: Oral presentation.

Gabryszewski SJ, Dudley J, Grundmeier RW, Fiks AG, Spergel JM, Hill DA: Food Allergy Documentation Patterns in Children in the Era of Early Food Introduction. American Academy of Allergy, Asthma & Immunology Annual Meeting, Washington, DC; The Journal of Allergy and Clinical Immunology Feb 2024 Notes: Poster presentation.

Rodríguez-López EM, Clement R, Lal M, Ruffner M, Eisenlohr L, Hill DA: Epithelial cell-intrinsic MHCII regulates esophageal food allergy in an IFNγ-dependent manner. American Academy of Allergy, Asthma & Immunology Annual Meeting, Washington, DC; The Journal of Allergy and Clinical Immunology Feb 2024 Notes: Poster presentation.

McCright S, Young L, Hill DA: Dietary saturated fatty acids alter lung innate immune responses to allergic stimuli. American Academy of Allergy, Asthma & Immunology Annual Meeting, Washington, DC; The Journal of Allergy and Clinical Immunology Feb 2024 Notes: Poster presentation.

Chini J, McCright S, Hill DA: Hepatic CD9 regulates immune cell activation and metabolic dysfunction during obesity. American Academy of Allergy, Asthma & Immunology Annual Meeting, Washington, DC; The Journal of Allergy and Clinical Immunology Feb 2024 Notes: Poster presentation.

Clement R, Rodríguez-López EM, Dilollo J, Guerrier C, Hill DA: IFNү impairs regulatory B cell function during Eosinophilic Esophagitis. American Academy of Allergy, Asthma & Immunology Annual Meeting, Washington, DC; The Journal of Allergy and Clinical Immunology Feb 2024 Notes: Poster presentation.

Senter JP, Aisenberg LK, Dudley J, Luan X, Huang J, Kenyon CC, Hill DA: Lack of association between SARS-CoV-2 PCR positivity and subsequent asthma diagnosis in a pediatric cohort. American Academy of Allergy, Asthma & Immunology Annual Meeting, Washington, DC; The Journal of Allergy and Clinical Immunology Feb 2024 Notes: Poster presentation.

Grier AE, Hill DA: Severe, life-threatening hereditary angioedema of the larynx induced by ingestion of cold foods. American College of Allergy, Asthma & Immunology Annual Meeting, Anaheim, CA; Annals of Allergy, Asthma & Immunology Nov 2023 Notes: Poster presentation.

Hill DA, Muir AB.: The immune-epithelial interface in eosinophilic esophagitis: a conversation. Frontiers in Allergy 4, Oct 2023.

Paneru B, Hill DA: The role of extracellular vesicle-derived miRNAs in adipose tissue function and metabolic health. Immunometabolism 5(3), Jul 2023.