Faculty

Thomas H. Leung, M.D., Ph.D.

Herman Beerman, MD II Professor in Dermatology

Department: Dermatology

Graduate Group Affiliations

Contact information

421 Curie Boulevard
1001 Biomedical Research Building II/III, Room 1006
Philadelphia, PA 19104

Email:
thl@pennmedicine.upenn.edu

Education:
B.S. (Biological Sciences)
Stanford University, Stanford, CA, 1998.
Ph.D. (Biology)
California Institute of Technology, Pasadena, CA, 2005.
M.D. (Medicine)
UCLA School of Medicine, Los Angeles, CA, 2007.

Links
Thomas Leung Lab

Permanent link

> Perelman School of Medicine > Faculty > Details

Selected Publications

Rapp E., Pang J., Saeednia B., Prouty S.M., Reilly C.A., and Leung T.H.: Carnosic acid in topical rosemary extract enhances skin repair via TRPA1 activation. JCI Insight 10(23), Oct 2025.

Huang J., Sati S., Ahart O., Rapp-Reyes E., Zhou L., Micheletti R.G., James W, Rosenbach M, and Leung T.H. : SAA1/FPR2 signaling between keratinocytes and neutrophils sustains chronic inflammation in Sweet syndrome. J Clin Invest 135(20), Aug 2025.

Zhou L. and Leung T.H.: Detection by single-cell RNA-sequencing of virally-mediated skin diseases. JID Innovations 5(3), Jan 2025.

Huang J., Sati S., Murphy C., Spencer C.A., Rapp E., Prouty S., Korte S., Ahart O., Sheng E., Jones P., Kersh A., Leung D., and Leung T.H. : Granulocyte-colony stimulating factor promotes scarless tissue regeneration. Cell Reports 43(10): 114742, Sep 21 2024.

Chen B., He B., Tucker A.M., Biluck I., Leung T.H., Schaer T.P., and Yang S.: An Environmentally Stable, Biocompatible, and Multilayered Wound Dressing Film with Reversible and Strong Adhesion. Advanced Healthcare Materials Page: e2400827, Sep 12 2024 Notes: Online ahead of print.

Sati S, Jones P, Kersh A, Murphy C, Hedberg ML, Huang J, Jain V, Gregory SG, Leung DH, Rosenbach M., and Leung T.H. : Recruitment of CXCR4+ type 1 innate lymphoid cells distinguishes sarcoidosis from other skin granuloma diseases. J Clin Invest 134(17): e179711, Sep 3 2024.

Kersh A., Sati S., Murphy C., Ahart O., and Leung T.H. : CXCL9, CXCL10, and CCL19 synergistically recruit T-lymphocytes to skin in lichen planus. JCI Insight Page: e179899, Aug 27 2024.

Bhattacharya S., Sheng E., Murphy C., Wei J., Kersh A., Nelson C.A., Bryer J.S., Ashchyan H.A., Steele K., Forrestel A., Seykora J.T., Micheletti R.G., James W.D., Rosenbach M., and Leung T.H. : Treatment of Sweet Syndrome Guided by Molecular Identification of PIK3R1 mutation. JCI 133(1): e162137, Jan 2023.

Sati S., Jones P., Kim H.S., Zhou L.A., Rapp-Reyes E., and Leung T.H. : HiCuT: An efficient and low input method to identify protein-directed chromatin interactions. PLOS Genetics 18(3): e1010121, Mar 23 2022 Notes: doi: 10.1371/journal.pgen.1010121.

Peraramelli S., Zhou Q., Zhou Q., Wanko B., Zhao L., Nishimura T., Leung T.H., Mizuno S., Ito M., Myles T., Stulnig T.M., Morser J., and Leung L.L. : Thrombin cleavage of osteopontin initiates osteopontin’s tumor-promoting activity. J Thromb Haemost 20(5): 1256-1270, Feb 2 2022 Notes: doi: 10.1111/jth.15663. Online ahead of print.