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Faculty

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Daniel H. Wolf, M.D., Ph.D.

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Associate Professor of Psychiatry
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Department: Psychiatry
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1f Graduate Group Affiliations 8 a
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Richards Building, Room A506
22 University of Pennsylvania
35 3700 Hamilton Walk
Philadelphia, PA 19104
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2e Office: 215-662-3692
32 Fax: 215-662-7903
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13 Education:
21 9 A.B. 14 (Biology) c
28 Harvard College, 1992.
21 a Ph.D. 19 (Neuroscience) c
3b Yale University School of Medicine, 2000.
21 9 M.D. 15 (Medicine) c
3b Yale University School of Medicine, 2001.
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Description of Research Expertise

1a Key Words
57 psychosis, reward, motivation, negative symptoms, fMRI, pharmacological imaging
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34 Research interests, techniques, and summary:
2dc My overarching goal is to develop a translational research program to study the neural mechanisms of reward and motivation deficits in psychosis, depression, addiction, and other psychiatric disorders, and in those at risk for these disorders. By utilizing pharmacological challenges during functional neuroimaging, together with detailed clinical and behavioral assessments, I seek to relate these deficits to dysfunction in specific neural circuits, and develop better methods for assessing novel therapeutic interventions. I am also developing active collaborations with geneticists, animal researchers, and pharmaceutical industry scientists in order facilitate clinical translation of basic neuroscientific discoveries.
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Description of Clinical Expertise

8a Dr. Wolf is a board-certified psychiatrist, with particular expertise in the treatment of adults with psychotic disorders.
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26 Last updated: 10/19/2025
34 The Trustees of the University of Pennsylvania c
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