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Laboratory of Rare Lung Diseases
3e 3b 48Reynold A. Panettieri, jr.
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Reynold A. Panettieri, Jr.
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Emeritus Professor of Medicine
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Department: Medicine
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Contact information
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University of Pennsylvania
1d 125 South 31st Street
36 TRL Suite 1200
Philadelphia, PA 19104-3413
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1d 125 South 31st Street
36 TRL Suite 1200
Philadelphia, PA 19104-3413
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Office: (215) 573-9860
34 Fax: (215) 746-1224
34 Lab: (215) 746-2759
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34 Fax: (215) 746-1224
34 Lab: (215) 746-2759
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Email:
rap@mail.med.upenn.edu
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rap@mail.med.upenn.edu
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Education:
21 9 B.S. 14 (Biology) c
42 St. Joseph's University, Philadelphia, PA, 1979.
21 9 M.D. 15 (Medicine) c
33 University of Pennsylvania, 1983.
21 9 M.A. 15 (Honorary) c
33 University of Pennsylvania, 1998.
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Permanent link21 9 B.S. 14 (Biology) c
42 St. Joseph's University, Philadelphia, PA, 1979.
21 9 M.D. 15 (Medicine) c
33 University of Pennsylvania, 1983.
21 9 M.A. 15 (Honorary) c
33 University of Pennsylvania, 1998.
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Description of Research Expertise
61 Smooth muscle biology, airway remodeling, respiratory pharmacology and physiology65
Description of Clinical Expertise
5e Asthma, chronic obstructive pulmonary disease, irreversible airway obstruction1a 29
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234 McGeachie Michael J, Wu Ann C, Tse Sze Man, Clemmer George L, Sordillo Joanne, Himes Blanca E, Lasky-Su Jessica, Chase Robert P, Martinez Fernando D, Weeke Peter, Shaffer Christian M, Xu Hua, Denny Josh C, Roden Dan M, Panettieri Reynold A, Raby Benjamin A, Weiss Scott T, Tantisira Kelan G: CTNNA3 and SEMA3D: Promising loci for asthma exacerbation identified through multiple genome-wide association studies. The Journal of allergy and clinical immunology 136(6): 1503-1510, December 2015.
f3 Panettieri Reynold A: Bronchial Thermoplasty: Targeting Structural Cells in Severe Persistent Asthma. Annals of the American Thoracic Society 12(11): 1593-1594, Nov 2015.
118 Liao Guoning, Panettieri Reynold A, Tang Dale D: MicroRNA-203 negatively regulates c-Abl, ERK1/2 phosphorylation, and proliferation in smooth muscle cells. Physiological reports 3(9): e12541, September 2015.
185 Panettieri, R.A., Jr.: New details on family poisoned by pesticide. CNN, http://www.cnn.com/2015/09/10/us/virgin-islands-pesticide-investigation/index.html?sr=fb091015familypoisoned3pVODtopLink. September 2015 Notes: Interviewed by CNN Correspondent Sara Ganim Regarding Family Exposed to Methyl Bromide, June 2015
14a Panettieri, R.A., Jr.: Radio Interview Re: Cardiovascular hospitalizations in hydrofracking areas. WPEL Radio, Montrose, PA September 2015 Notes: Larry Souder, WPEL Radio, Montrose, PA, interviewed Dr. Panettieri on 9/2/15; the interviewed aired on 9/26/15.
d4 Panettieri Reynold A: Bronchodilators, receptors and cross-talk: together is better? Postgraduate medicine 127(7): 771-780, September 2015.
1d1 Kohli Puja, Pinto-Plata Victor, Divo Miguel, Malhotra Atul, Harris R Scott, Lazaar Aili, Flynn Aiden, Tal-Singer Ruth, Panettieri Reynold A, Celli Bartolome: Functional Capacity, Health Status, and Inflammatory Biomarker Profile in a Cohort of Patients With Chronic Obstructive Pulmonary Disease. Journal of cardiopulmonary rehabilitation and prevention 35(5): 348-55, September-October 2015.
1ae Sun Yan, Jain Deepika, Koziol-White Cynthia J, Genoyer Emmanuelle, Gilbert Micah, Tapia Karla, Panettieri Reynold A, Hodinka Richard L, López Carolina B: Immunostimulatory Defective Viral Genomes from Respiratory Syncytial Virus Promote a Strong Innate Antiviral Response during Infection in Mice and Humans. PLoS pathogens 11(9): e1005122, September 2015.
178 Panettieri, R.A., Jr., Brightling, C., Sjobring, U., Peterffy, A., Tornling, G., Daoud, S.Z., Ranade, K., Hollis, S., Colice, G.: STRATOS 1 and 2: considerations in clinical trial design for a fully human monoclonal antibody in severe asthma. Clinical Investigation (London) 5(8): 701-711, August 2015.
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Selected Publications
160 Carr Richard, Koziol-White Cynthia, Zhang Jie, Lam Hong, An Steven S, Tall Gregory G, Panettieri Reynold A, Benovic Jeffrey L: Interdicting Gq Activation in Airway Disease by Receptor-Dependent and Receptor-Independent Mechanisms. Molecular pharmacology 89: 94-104, January 2016.234 McGeachie Michael J, Wu Ann C, Tse Sze Man, Clemmer George L, Sordillo Joanne, Himes Blanca E, Lasky-Su Jessica, Chase Robert P, Martinez Fernando D, Weeke Peter, Shaffer Christian M, Xu Hua, Denny Josh C, Roden Dan M, Panettieri Reynold A, Raby Benjamin A, Weiss Scott T, Tantisira Kelan G: CTNNA3 and SEMA3D: Promising loci for asthma exacerbation identified through multiple genome-wide association studies. The Journal of allergy and clinical immunology 136(6): 1503-1510, December 2015.
f3 Panettieri Reynold A: Bronchial Thermoplasty: Targeting Structural Cells in Severe Persistent Asthma. Annals of the American Thoracic Society 12(11): 1593-1594, Nov 2015.
118 Liao Guoning, Panettieri Reynold A, Tang Dale D: MicroRNA-203 negatively regulates c-Abl, ERK1/2 phosphorylation, and proliferation in smooth muscle cells. Physiological reports 3(9): e12541, September 2015.
185 Panettieri, R.A., Jr.: New details on family poisoned by pesticide. CNN, http://www.cnn.com/2015/09/10/us/virgin-islands-pesticide-investigation/index.html?sr=fb091015familypoisoned3pVODtopLink. September 2015 Notes: Interviewed by CNN Correspondent Sara Ganim Regarding Family Exposed to Methyl Bromide, June 2015
14a Panettieri, R.A., Jr.: Radio Interview Re: Cardiovascular hospitalizations in hydrofracking areas. WPEL Radio, Montrose, PA September 2015 Notes: Larry Souder, WPEL Radio, Montrose, PA, interviewed Dr. Panettieri on 9/2/15; the interviewed aired on 9/26/15.
d4 Panettieri Reynold A: Bronchodilators, receptors and cross-talk: together is better? Postgraduate medicine 127(7): 771-780, September 2015.
1d1 Kohli Puja, Pinto-Plata Victor, Divo Miguel, Malhotra Atul, Harris R Scott, Lazaar Aili, Flynn Aiden, Tal-Singer Ruth, Panettieri Reynold A, Celli Bartolome: Functional Capacity, Health Status, and Inflammatory Biomarker Profile in a Cohort of Patients With Chronic Obstructive Pulmonary Disease. Journal of cardiopulmonary rehabilitation and prevention 35(5): 348-55, September-October 2015.
1ae Sun Yan, Jain Deepika, Koziol-White Cynthia J, Genoyer Emmanuelle, Gilbert Micah, Tapia Karla, Panettieri Reynold A, Hodinka Richard L, López Carolina B: Immunostimulatory Defective Viral Genomes from Respiratory Syncytial Virus Promote a Strong Innate Antiviral Response during Infection in Mice and Humans. PLoS pathogens 11(9): e1005122, September 2015.
178 Panettieri, R.A., Jr., Brightling, C., Sjobring, U., Peterffy, A., Tornling, G., Daoud, S.Z., Ranade, K., Hollis, S., Colice, G.: STRATOS 1 and 2: considerations in clinical trial design for a fully human monoclonal antibody in severe asthma. Clinical Investigation (London) 5(8): 701-711, August 2015.
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