Liane Miller, MD

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Assistant Professor of Orthopaedic Surgery at the Hospital of the University of Pennsylvania
Department: Orthopaedic Surgery

Contact information
Perelman School of Medicine at the University of Pennsylvania
3737 Market Street, 6th Floor
Philadelphia, PA 19104
Education:
B.S. (Cellular and Developmental Biology )
University of California, Santa Barbara, 2008.
M.D. (Medicine)
University of California, San Francisco School of Medicine, 2016.
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Description of Clinical Expertise

Knee arthroscopy
Knee ligament reconstruction
Meniscus surgery
Knee tendon repairs
Patellofemoral instability
Cartilage restoration
Shoulder arthroscopy
Rotator cuff repair
Shoulder labrum repair
Shoulder dislocation/instability
Frozen shoulder
Acromioclavicular joint injuries
Distal biceps repair
Elbow ligement repair/reconstruction
Hip arthroscopy
Hip labrum repair/reconstruction
Proximal hamstring repair
Abductor repair
Trochanteric bursectomy

Description of Research Expertise

Meniscus and Cartilage Biology
Molecular Mechanisms of Regeneration and Repair
Translational Models of Musculoskeletal Disease

Selected Publications

Bernstein ER, Stoeckl BD, Flaugh R, Laforest L, Burt KG, Dyment NA, Scanzello CR, Mauck RL, Miller L.: Inhibition of fibroblast activation protein partially restores the homeostatic phenotype of mechanoactivated synoviocytes. Osteoarthritis Cartilage Mar 2026.

Sontam TR, Tummala S, Khela HS, Miller L, Kelly JD 4th.: Cannabis use disorder is associated with increased early postoperative opioid use and pain but no long-term differences after arthroscopic rotator cuff repair: a retrospective cohort study using TriNetX. J Shoulder Elbow Surg Mar 2026.

Guattery J, Miller LM, Irrgang JJ, Lin A, Parmanto B, Tafti AP.: Explainable machine learning to predict prolonged post-operative opioid use in rotator cuff patients. BMC Musculoskelet Disord 26: 1094, Dec 2025.

Khela HS, Khela MS, Kelly JD 4th, Miller L.: Effect of Mental Health Diagnoses on Postoperative Outcomes and Secondary Treatment Utilization After Surgery for Adhesive Capsulitis: A Retrospective Large Database Analysis. J Am Acad Orthop Surg Glob Res Rev 9: e24, Oct 2025.

Khela HS, Khela MS, Jose J, Madi R, Kelly JD 4th, Miller L.: Treatment and Clinical Outcomes of Tibial Spine Fractures in Adults: A Systematic Review and Meta-Analysis. Orthopedics May 2025.

Khela HS, Khela MS, Kelly JD 4th, Miller L.: Metabolic Syndrome is Associated with Increased Complications and Healthcare Costs After Adhesive Capsulitis Surgery. J Shoulder Elbow Surg May 2025.

Locke RC, Miller LM, Lemmon EA, Assi SS, Jones DL, Bonnevie ED, Burdick JA, Heo SJ, Mauck RL.: Rapid restoration of cell phenotype and matrix forming capacity following transient nuclear softening. Acta Biomater 2025.

Fujino K, Keith S, Kamalitdinov TB, Madi R, Jiang X, Zgonis MH, Miller LM, Kuntz AF, Dyment NA.: Compressive Graft Fit Promotes Tendon-to-Bone Integration After Anterior Cruciate Ligament Reconstruction. Am J Sports Med 2025.

Miller LM, Bernstein ER, Scanzello CR, Mauck RL.: Synovial changes in osteoarthritis: symptom or disease driver? Connect Tissue Res 2025.

Loya D, Kaarre J, Marcaccio SE, Nazzal EM, Como CJ, Herman ZJ, Miller LM, Musahl V.: Revision Anterior Cruciate Ligament Reconstruction in Combination With Meniscal and Osteochondral Allograft Transplantation for Complex Knee Injury. Arthrosc Tech 14: 103157, Aug 2024.

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Last updated: 05/15/2026
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