Nathaniel Dyment

faculty photo
Assistant Professor of Orthopaedic Surgery
Department: Orthopaedic Surgery

Contact information
McKay Orthopaedic Research Laboratory
330A Stemmler Hall
3450 Hamilton Walk
Philadelphia, PA 19104-6081
Office: 215-746-8138
Fax: 215-573-2133
Lab: 215-746-8167
Education:
B.S. (Materials Science and Engineering)
University of Illinois at Urbana-Champaign , 2005.
Ph.D. (Biomedical Engineering)
University of Cincinnati, 2011.
Permanent link
 
> Perelman School of Medicine   > Faculty   > Details

Description of Research Expertise

My primary research goals are directed towards understanding the genetic, cellular, and mechanical mechanisms that regulate normal development, disease (e.g., chronic tendon pathologies, osteoarthritis, psoriatic arthritis, ankylosing spondylitis), and repair of tissues in the joint. My current research focuses on 1) identifying the resident progenitor populations that contribute to normal growth, healing and repair, 2) characterizing the mechanisms that control the expansion and differentiation of these cells, and 3) ascertaining the phenotypical markers that define the stages of differentiation from early stem/progenitors to mature tendon/ligament fibroblasts and chondrocytes. These goals in combination will guide future therapeutic strategies and provide success criteria to assess efficacy moving forward.

Selected Publications

Xi Jiang; Catherine Bautista; Anjana Srikumar; Andrew Hendrix; Courtney Thompson; Alexander Kuang; Andrew Kim; Nathaniel Dyment: Collagen And Prg4 Fluorescent Reporter Mice Establish Unique Subsets Of Tendon Fibroblasts. Orthopaedic Research Society Annual Meeting February 2020.

Wei-Ju Tseng; Wenzheng Wang; Hongbo Zhao; Alexander Bennett; Lisa Mariani; Yihan Li; Nathaniel Dyment; Do-Gyoon Kim; Kevin Turner; X. Sherry Liu: Differences In Material Properties Of Trabecular Bone Tissue From Modeling- And Remodeling-Based Bone Formation In Rats. Orthopaedic Research Society Annual Meeting February 2020.

Caleb Jones; Joseph M. Collins; Jong Hyun (Thomas) Kim; Nathaniel Dyment; Joel D. Boerckel: Quantitative Spatial Mapping Of Osteoblast Lineage Progression In Embryonic Development. Orthopaedic Research Society Annual Meeting February 2020.

Anupama Prabhath; Varadraj Vernekar; Ellen Eisenberg; Mary Badon; Takayoshi Otsuka; Godwin Dzidotor; Jean- Emmanuel Avochinou; Sangamesh Kumbar; Nathaniel Dyment; Stavros Thomopoulos; Eckhard Weber; Cato Laurencin: Rotator Cuff Enthesis Regeneration Via Engineered Delivery of Insulin-like Growth Factor-1 Mimics. Orthopaedic Research Society Annual Meeting February 2020.

Yilu Zhou; Yihan Li; Zachary Davis; Wenzheng Wang; Ashley K. Fung; Snehal S. Shetye; Xi Jiang; Andrew F. Kuntz; Nathaniel Dyment; Louis J. Soslowsky; X. Sherry Liu: Structural And Cellular Responses Of Supraspinatus Tendon Enthesis And Subchondral Bone To Pregnancy, Lactation, And Post-Weaning Recovery. Orthopaedic Research Society Annual Meeting February 2020.

Wenzheng Wang; Wei-Ju Tseng; Hongbo Zhao; Tala Azar; Nathaniel Dyment; X. Sherry Liu: Dynamics Of Modeling- And Remodeling-Based Bone Formation In Response To Intermittent Parathyroid Hormone (PTH) Treatment And Discontinuation. Orthopaedic Research Society Annual Meeting February 2020.

Tonia Tsinman; Xi Jiang; Lin Han; Eiki Koyama; Robert Mauck; Nathaniel Dyment: Cellular Dynamics And Zonal Specialization Of The Murine Meniscus ECM During Postnatal Growth. Orthopaedic Research Society Annual Meeting February 2020.

Joseph M. Collins; Nathaniel Dyment; Joel D. Boerckel: Yap And Taz Coordinate Endochondral Bone Development. Orthopaedic Research Society Annual Meeting February 2020.

Catherine A. Bautista; Xi Jiang; Kyu Sang Joeng; Nathaniel A. Dyment: F4/80 Tendon Resident Macrophages And Potential Cross-talk With Tendon Fibroblasts During Growth. Orthopaedic Research Society Annual Meeting February 2020.

Timur B. Kamalitdinov; Keitaro Fujino; Xi Jiang; Andrew F. Kuntz; Miltiadis H. Zgonis; Nathaniel A. Dyment: Hedgehog Signaling Regulates Tunnel Integration Following ACL Reconstruction. Orthopaedic Research Society Annual Meeting February 2020.

back to top
Last updated: 02/26/2020
The Trustees of the University of Pennsylvania
 
Back to Top