Selina M. Luger

faculty photo
Professor of Medicine at the Hospital of the University of Pennsylvania
Attending Physician , Hospital of the University of Pennsylvania
Member , Abramson Cancer Center, University of Pennsylvania
Director, Leukemia Program, Abramson Cancer Center, Perelman School of Medicine
Medical Board, Member, Executive Committee, Hospital of the University of Pennsylvania
Medical Board, President , Hospital of the University of Pennsylvania
Department: Medicine

Contact information
Division of Hematology Oncology
Perelman Center for Advanced Medicine
12th Floor, South Pavilion
Office #12-101
34th and Civic Center Blvd
Philadelphia, PA 19104
Office: 215-614-1847
Fax: 215-662-4064
Education:
A.B. (Biochemistry)
Harvard University, 1982.
M.D.CM (Medicine)
McGill University, 1987.
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Description of Research Expertise

Leukemia, myelodysplastic syndrome, myeloproliferative disorders
MDS, AML, CML, ALL

Description of Itmat Expertise

Dr. Luger conducts translational research in leukemia, MDS and other hematologic malignancies.

Selected Publications

Kasner MT, Mick R, Jeschke GR, Carabasi M, Filicko-O'Hara J, Flomenberg N, Frey NV, Hexner EO, Luger SM, Loren AW, Mangan JK, Wagner JL, Weiss M, Carroll M, Perl AE: Sirolimus enhances remission induction in patients with high risk acute myeloid leukemia and mTORC1 target inhibition. Invest New Drugs. 36(4): 657-666, Aug 2018.

Siegel SE, Advani A, Seibel N, Muffly L4, Stock W, Luger S, Shah B, DeAngelo DJ, Freyer DR, Douer D, Johnson RH, Hayes-Lattin B, Lewis M, Jaboin JJ, Coccia PF, Bleyer A.: Treatment of young adults with Philadelphia-negative acute lymphoblastic leukemia and lymphoblastic lymphoma: Hyper-CVAD vs. pediatric-inspired regimens. Am J Hematol. Jul 2018 Notes: Epub ahead of print.

Crisalli LM, Hinkle JT, Walling CC, Sell M, Frey NV, Hexner EO, Loren AW, Luger SM, Stadtmauer EA, Porter DL, Reshef R: Higher Donor Apheresis Blood Volumes Are Associated with Reduced Relapse Risk and Improved Survival in Reduced-Intensity Allogeneic Transplantations with Unrelated Donors. Biol Blood Marrow Transplant. 24(6): 1203-1208, Jun 2018.

Ganzel C, Sun Z, Cripe LD, Fernandez HF, Douer D, Rowe JM, Paietta EM, Ketterling R, O'Connell MJ, Wiernik PH, Bennett JM, Litzow MR, Luger SM, Lazarus HM, Tallman MS: Very poor long-term survival in past and more recent studies for relapsed AML patients: The ECOG-ACRIN experience. Am J Hematol. Jun 15 2018 Notes: Epub ahead of print.

Siegel SE, Stock W, Johnson RH, Advani A, Muffly L, Douer D, Reed D, Lewis M, Freyer DR, Shah B, Luger S, Hayes-Lattin B, Jaboin JJ, Coccia PF, DeAngelo DJ, Seibel N, Bleyer A: Pediatric-Inspired Treatment Regimens for Adolescents and Young Adults With Philadelphia Chromosome-Negative Acute Lymphoblastic Leukemia: A Review. JAMA Oncol. 4(5): 725-734, May 2018.

Ganetsky A, Frey NV, Hexner EO, Loren AW, Gill SI, Luger SM, Mangan JK, Martin ME, Babushok DV, Drobyski WR, Smith J, Timlin C, Freyer CW, Stadtmauer EA, Porter DL.: Tocilizumab for the treatment of severe steroid-refractory acute graft-versus-host disease of the lower gastrointestinal tract. Bone Marrow Transplant. May 2018 Notes: Epub ahead of print.

Stahl M, Pine A, Hendrickson JE, Litzow MR, Luger SM, Stone RM, Erba HP, Kim TK, Sekeres MA, Steensma DP, Komrokji RS, Gore SD, Zeidan AM.: Beliefs and practice patterns in hyperleukocytosis management in acute myeloid leukemia: a large U.S. web-based survey. Leuk Lymphoma. April 2018 Notes: Epub ahead of print.

Tasian SK1, Hurtz C2, Wertheim GB3, Bailey NG4, Lim MS4, Harvey RC5, Chen IM5, Willman CL5, Astles R2, Zebrowski A2, Reshmi SC6, Li MM7, Frey NV2, Luger SM2, Carroll M2, Perl AE2.: High incidence of Philadelphia chromosome-like acute lymphoblastic leukemia in older adults with B-ALL. Leukemia. 31(4): 981-984, Apr 2017

Miller Tamara P, Li Yimei, Kavcic Marko, Getz Kelly D, Huang Yuan-Shun V, Sung Lillian, Alonzo Todd A, Gerbing Robert, Daves Marla H, Horton Terzah M, Pulsipher Michael A, Pollard Jessica, Bagatell Rochelle, Seif Alix E, Fisher Brian T, Luger Selina, Gamis Alan S, Adamson Peter C, Aplenc Richard: Center-level variation in accuracy of adverse event reporting in a clinical trial for pediatric acute myeloid leukemia: a report from the Children's Oncology Group. Haematologica 102(9): e340-e343, Sep 2017.

Strickland Stephen A, Sun Zhuoxin, Ketterling Rhett P, Cherry Athena M, Cripe Larry D, Dewald Gordon, Fernandez Hugo F, Hicks Gary A, Higgins Rodney R, Lazarus Hillard M, Litzow Mark R, Luger Selina M, Paietta Elisabeth M, Rowe Jacob M, Vance Gail H, Wiernik Peter, Wiktor Anne E, Zhang Yanming, Tallman Martin S: Independent Prognostic Significance of Monosomy 17 and Impact of Karyotype Complexity in Monosomal Karyotype/Complex Karyotype Acute Myeloid Leukemia: Results from Four ECOG-ACRIN Prospective Therapeutic Trials. Leukemia research 59: 55-64, Aug 2017.

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Last updated: 09/28/2018
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