Adam Bagg

faculty photo
Professor of Pathology and Laboratory Medicine at the Hospital of the University of Pennsylvania
Attending in Hematopathology, Laboratory Hematology, Flow Cytometry and Molecular Pathology, Hospital of the University of Pennsylvania
Director, Hematology, Hospital of the University of Pennsylvania
Department: Pathology and Laboratory Medicine

Contact information
Department of Pathology and Laboratory Medicine
Hospital of the University of Pennsylvania
Division of Hematopathology
7.017 Gates Pavilion
3400 Spruce Street
Philadelphia, PA 19104-4283
Office: 215-662-4280
Fax: 215-615-3931
Education:
MB. BCh (magna cum laude)
University of the Witwatersrand, South Africa, Top 1% of graduating class, 1981.
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Description of Research Expertise

Molecular genetics and pathology of Leukemias and Lymphomas; Myelodysplastic syndromes; Minimal residual disease; Hodgkin lymphoma

Description of Itmat Expertise

Dr. Bagg studies: (1) the diagnostic molecular pathology of hematologic malignancies, with the development of novel assays to facilitate their diagnosis; (2) minimal residual disease testing in leukemia, lymphoma and myeloma; and (3) unraveling the biology and improving the laboratory diagnosis of the myelodysplastic syndromes.

Selected Publications

160. Ohgami RS, Rosenwald A, Bagg A: Next-Generation Sequencing for Lymphomas: Perfecting a Pipeline for Personalized Pathobiologic and Prognostic Predictions. Journal of Molecular Diagnostics 2018.

Kim MY, Yu KR, Kenderian SS, Ruella M, Chen S, Shin TH, Aljanahi AA, Schreeder D, Klichinsky M, Shestova O, Kozlowski MS, Cummins KD, Shan X, Shestov M, Bagg A, Morrissette JJD, Sekhri P, Lazzarotto CR, Calvo KR, Kuhns DB, Donahue RE, Behbehani GK, Tsai SQ, Dunbar CE, Gill S. : Genetic Inactivation of CD33 in Hematopoietic Stem Cells to Enable CAR T Cell Immunotherapy for Acute Myeloid Leukemia. Cell 173: 1439-1453, May 2018.

Aynardi J, Manur R, Hess PR, Chekol S, Morrissette JJD, Babushok D, Hexner E, Rogers HJ, Hsi ED, Margolskee E, Orazi A, Hasserjian R, Bagg A. : JAK2 V617F-positive acute myeloid leukaemia (AML): a comparison between de novo AML and secondary AML transformed from an underlying myeloproliferative neoplasm. A study from the Bone Marrow Pathology Group. Br J Haematol. 182: 78-85, July 2018.

Rea B, Haun P, Emerson R, Vignali M, Farooqi M, Samimi S, Elenitsas R, Kirsch I, Bagg A. : Role of high-throughput sequencing in the diagnosis of cutaneous T-cell lymphoma. J Clin Pathol. 71: 814-820, September 2018.

Wang J, Rea B, Haun P, Emerson R, Kirsch I, Bagg A. : High-Throughput Sequencing of the T-cell receptor beta chain gene distinguishes two subgroups of cutaneous T-cell lymphoma. Journal of the American Academy of Dermatology 80: 1148-1150, April 2018.

Sadigh S, Morrissette JJD, Bagg A. : FBXW7 mutations in acute myeloid leukemia. Leuk Lymphoma 60: 1601-1602, June 2019.

Salehi S, Astle JM, Sadigh S, Lake J, Aikawa V, Tang G, Wang SA, Bagg A.: Myeloid neoplasm with eosinophilia and PCM1-JAK2 associated with acute promyelocytic leukemia with PML-RARA. Leuk Lymphoma. 60: 2299-2303, September 2019.

Kluk MJ, Bagg A: Expedited analysis and reporting of multiple mutations that modify medical management in myeloid malignancies: It's about (turn-around) time! Journal of Molecular Diagnostics 2019.

Caponetti GC, Bagg A: Genetic studies in the evaluation of myeloproliferative neoplasms. Semin Hematol. 2019.

Baraban E, Sadigh S, Rosenbaum J, Van Arnam J, Bogusz AM, Mehr C, Bagg A.: Cyclin D1 expression and novel mutational findings in Rosai-Dorfman disease. Br J Haematol. 186: 837-844, September 2019.

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Last updated: 07/23/2020
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