Giorgos C Karakousis
Professor of Surgery at the Hospital of the University of Pennsylvania
Attending Staff Surgeon, Hospital of the University of Pennsylvania, Philadelphia, PA
Full Researcher Member, Abramson Cancer Center, University of Pennsylvania Health System, Philadelphia, PA
Chair, Cancer Committee, Abramson Cancer Center, Perelman School of Medicine, Philadelphia, PA
Site Co-Team Leader, Melanoma Disease, Abramson Cancer Center, Penn Medicine, Philadelphia, PA
Chief, Division of Endocrine & Oncologic Surgery, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA
Department: Surgery
Contact information
Division of Endocrine & Oncologic Surgery
Hospital of the University of Pennsylvania
3400 Spruce St., 4 Silverstein
Philadelphia, PA 19104
Hospital of the University of Pennsylvania
3400 Spruce St., 4 Silverstein
Philadelphia, PA 19104
Office: 215-662-2083
Fax: 215-662-7476
Fax: 215-662-7476
Education:
BS, MS (Molecular Biophysics and Biochemistry)
Yale University, 1996.
MD
University of Pennsylvania School of Medicine, 2001.
BS, MS (Molecular Biophysics and Biochemistry)
Yale University, 1996.
MD
University of Pennsylvania School of Medicine, 2001.
Post-Graduate Training
Internship in General Surgery, University of Pennsylvania School of Medicine, Philadelphia, PA, 2001-2002.
Residency in General Surgery, University of Pennsylvania School of Medicine, Philadelphia, PA, 2002-2008.
Post-Doctoral Research Fellow, Harrison Department of Surgical Research, University of Pennsylvania School of Medicine, Philadelphia, PA, 2004-2006.
Fellowship in Surgical Oncology, Department of Surgery, Memorial Sloan-Kettering Cancer Center, New York, NY, 2008-2010.
Permanent linkInternship in General Surgery, University of Pennsylvania School of Medicine, Philadelphia, PA, 2001-2002.
Residency in General Surgery, University of Pennsylvania School of Medicine, Philadelphia, PA, 2002-2008.
Post-Doctoral Research Fellow, Harrison Department of Surgical Research, University of Pennsylvania School of Medicine, Philadelphia, PA, 2004-2006.
Fellowship in Surgical Oncology, Department of Surgery, Memorial Sloan-Kettering Cancer Center, New York, NY, 2008-2010.
Description of Itmat Expertise
Melanoma--prognostic biomarkers; immune biomarkers; clinical trials for patients with locally advanced melanoma (isolated limb infusion trial with neoadjuvant ipilumamb); neoadjuvant anti-PD1 trial for clinical stage III melanomaSelected Publications
Wagner P, Levine EA, Kim AC, Shen P, Fleming ND, Westin SN, Berry LK, Karakousis GC, Tanyi JL, Olson MT, Madajewski B, Ostrander B, Krishnan K, Balch CM, Bartlett DL: Detection of residual peritoneal metastases following cytoreductive surgery using pegsitacianine, a pH-sensitive imaging agent: Final results from a phase II study. Annals of Surgical Oncology Apr. 15 2024 (Epub) Notes: doi: 10.1245/s10434-024-15165-4.Tortorello GN, Li EH, Sharon CE, Shafique N, Chu EY, Ming ME, Karakousis GC: Pathologic characteristics and clinical outcomes of primary dermal melanoma. Journal of the American Academy of Dermatology Feb. 23 2024 (Epub) Notes: doi: 10.1016/j.jaad.2024.01.082.
Vargas GM, Shafique N, Xu X, Karakousis G: Tumor-infiltrating lymphocytes as a prognostic and predictive factor for melanoma. Expert Review of Molecular Diagnostics Feb. 5 2024 (Epub) Notes: doi: 10.1080/14737159.2024.2312102.
Sharon CE, Karakousis GC: Neoadjuvant therapy for resectable melanoma. Clinical & Experimental Metastasis Jan. 28 2024 (Epub) Notes: doi: 10.1007/s10585-023-10263-1.
Maker AV, Karakousis G: Educating cancer-associated fibroblasts (CAFs): Are they the student or the teacher? Annals of Surgical Oncology 31(4): 2181-2182, Apr. 2024 Notes: Editorial; Epub Jan. 5, 2024.
Straker RJ 3rd, El Jack AK, Karakousis GC, Sharon CE, Ahmad NA, DeMatteo RP, Roses RE: Clinical features can distinguish gastrointestinal stromal tumor from other subepithelial gastric tumors. Journal of Gastrointestinal Surgery 28(3): 276-278, Mar. 2024 Notes: Research Communication; Epub Jan. 19, 2024.
Miura J, Sabharwal S, Ghert M, Karakousis G, Roland CL: Great debate: Systematic re-resection after macroscopic complete unplanned excision of soft tissue sarcoma. Annals of Surgical Oncology 31(3): 2047-2050, Mar. 2024 Notes: Epub Dec. 19, 2023.
Ma KL, Sharon CE, Tortorello GN, Keele L, Lukens JN, Karakousis GC, Miura JT: Delayed time to radiation and overall survival in Merkel cell carcinoma. Journal of Surgical Oncology 128(8): 1385-1393, Dec. 2023 Notes: Epub Aug. 25, 2023.
Sharon CE, Karakousis GC: Educational Review: Neoadjuvant approaches to melanoma. Annals of Surgical Oncology 29(13): 8492-8500, Dec. 2023 Notes: Epub July 18, 2022.
Rose MA, Miura J, Sharon C, Ermer JP, Karakousis G, Wachtel H: Current patterns of treatment and outcomes in advanced melanoma at a single institution. Journal of Surgical Oncology 291: 25-33, Nov. 2023 Notes: Epub June 16, 2023.