Michael John Bennett
Emeritus Professor CE of Pathology and Laboratory Medicine
Department: Pathology and Laboratory Medicine
Contact information
5NW58 CHOP Main Building
Philadelphia, PA 19104
Philadelphia, PA 19104
Office: 215-590-3394
Email:
bennettmi@email.chop.edu
bennettmi@email.chop.edu
Education:
BSc (Physiology & Biochemistry)
Reading University, UK, 1972.
PhD (Clinical Enzymology)
University of Sheffield School of Medicine, 1976.
BSc (Physiology & Biochemistry)
Reading University, UK, 1972.
PhD (Clinical Enzymology)
University of Sheffield School of Medicine, 1976.
Post-Graduate Training
Basic Grade Biochemist, Sheffield Central Hospitals, UK, 1975-1978.
Permanent linkBasic Grade Biochemist, Sheffield Central Hospitals, UK, 1975-1978.
Description of Research Expertise
Disorders of mitochondrial fatty acid oxidation with an emphasis on control of insulin secretion by short-chain 3-hydroxyacyl-CoA dehydrogenase deficiency. The Neuronal-Ceroid Lipofuscinoses. A stufdy of the function of CLN3P, the protein responsible for Juvenile Batten DiseaseDescription of Itmat Expertise
1. Define genetic defects of mitochondrial fatty acid oxidation, identify diagnostic biomarkers and study intramitochondrial compartmentalization of matrix proteins2. Study basic elements of neuronal death in neuronal ceroid-lipofuscinosis ( Batten disease) and develop an animal model to test therapies to prevent neuronal death