Steven M. Willi

faculty photo
Associate Professor of Pediatrics at the Children's Hospital of Philadelphia
Department: Pediatrics

Contact information
Division of Endocrinology
and Diabetes
The Children's Hospital
of Philadelphia
34th & Civic Center Blvd.
Philadelphia, PA 19104
Office: (215) 590-3618
Fax: (215) 590-3053
Education:
BA (Chemistry)
Johns Hopkins University, 1981.
MD (Medicine)
Johns Hopkins University, 1985.
Permanent link
 

Description of Itmat Expertise

Dr. Willi is interested in therapeutics for type 1 and type 2 diabetes and has performed a number of physiologic studies in the etiology and characterization of diabetes in children.
Current studies include three trials on the delay of progression of type 1 diabetes and a multicenter trial to examine the optimal therapeutics for type 2 diabetes in children.

Selected Publications

Rigby MR, Harris KM, Pinckney A, DiMeglio LA, Rendell MS, Felner EI, Dostou JM, Gitelman SE, Griffin KJ, Tsalikian E, Gottlieb PA, Greenbaum CJ, Sherry NA, Moore WV, Monzavi R, Willi SM, Raskin P, Keyes-Elstein L, Long SA, Kanaparthi S, Lim N, Phippard D, Soppe CL, Fitzgibbon ML, McNamara J, Nepom GT, Ehlers MR.: Alefacept provides sustained clinical and immunological effects in new-onset type 1 diabetes patients. J Clin Invest. 2015 Jul 20. pii: 81722 July 2015.

Shan Gao, Ming Li, Xiaoxue Qu, Yonghui Wang, Xiujuan Zhang, BCAMS, Steven M. Willi: ADA HbA1c Diagnostic Criteria Fail to Identify Prediabetes and Diabetes in a Population of Chinese Adoescents and Young Adults at High Risk for Diabetes. 75th Annual American Diabetes Association Meeting 64(Suppl. 1): A833, June 2015.

Rigby MR, Harris KM, Pinckney A, DiMeglio LA, Rendell MS, Felner EI, Dostou JM, Gitelman SE, Tsalikian E, Griffin KJ, Gottlieb PA, Greenbaum CJ, Sherry NA, Moore WV, Monzavi R, Willi SM, Raskin P, Keyes-Elstein L, Long S, Kanaparthi S, Lim N, Phippard D, Soppe CL, Fitzgibbon ML, McNamara J, Nepom GT, Ehlers MR; T1DAL Study Team.: Durable Efficacy of Alefacept in New-Onset Type 1 Diabetes: Evidence for Lasting Modulation of Effector and Regulatory T Cells. 75th Annual American Diabetes Association Meeting, Boston, MA 64(Suppl. 1): A231, June 2015.

Sosenko JM, Skyler JS, Beam CA, Boulware D, Mahon JL, Krischer JP, Greenbaum CJ, Rafkin LE, Matheson D, Herold KC, Palmer JP; Type 1 Diabetes TrialNet and Diabetes Prevention Trial–Type 1 Study Groups.: The development and utility of a novel scale that quantifies the glycemic progression toward type 1 diabetes over 6 months. Diabetes Care 38(5): 94-942, May 2015.

Ievers-Landis CE, Walders-Abramson N, Amodei N, Drews KL, Kaplan J, Levitt Katz LE, Lavietes S, Saletsky R, Seidman D, Yasuda P; Treatment Options for Type 2 Diabetes in Adolescents and Youth (TODAY) Study Group.: Longitudinal Correlates of Health Risk Behaviors in Children and Adolescents with Type 2 Diabetes. J Pediatr 166(5): 1258-1264, May 2015.

Klingensmith GJ, Connor CG, Ruedy KJ, Beck RW, Kollman C, Haro H< Wood JR, Lee JM, Willi SM, Cengiz E, Tamborlane WV; Pediatric Diabetes Consortium: Presentation of youth with type 2 diabetes in the Pediatric Diabetes Consortium. Pediatric Diabetes May 2015.

Weinstock RS, Trief, PA, El Ghormli L, Goland R< McKay S, Milaszewski K, Preske J, Willi S, Yasuda PM: Parental Characteristics Associated with Outcomes in Youth With Type 2 Diabetes: Results From the TODAY Clinical Trial. Diabetes Care 38(5): 784-792, May 2015.

Onengut-Gumuscu S, Chen WM, Burren O, Cooper NJ, Quinlan AR, Mychaleckyj JC< Farber E, Bonnie JK, Szpak M, Schofield E, Achuthan P, Guo H, Fortune MD, Stevens H, Walker NM, Ward LD, Kundaje A, Kellis M, Daly MJ, Barrett JC, Cooper JD, Deloukas P; Type 1 Diabetes Genetics Consortium (A Member),Todd JA, Wallace C, Concannon P, Rich SS: Fine mapping of type 1 diabetes susceptibility loci and evidence for colocalization of causal variants with lymphoid gene enhancers. Nature Genetics 47(4): 381-386, April 2015.

David Weber, Jennifer Kelley, Tammy Mawson, Steve Willi, Mary Leonard, and Babette Zemel: Sex Differences in Bone Density and Body Composition in Children Newly Diagnosed with Type 1 Diabetes. Endocrine Society Conference, San Diego, CA March 2015.

Tryggestad JB, Willi, SM: Complications and comorbidities of T2DM in adolescents: findings from the TODAY clinical trial. J Diabetes Complications 2: 307-312, March 2015.

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Last updated: 07/21/2015
The Trustees of the University of Pennsylvania