Max B. Kelz

faculty photo
David E. Longnecker Associate Professor of Anesthesiology and Critical Care
Member, Mahoney Institute of Neurological Sciences, University of Pennsylvania
Member, Penn Genomics Institute, University of Pennsylvania
Member, Institute for Translational Medicine and Therapeutics
Member, Center for Sleep and Circadian Neurobiology, University of Pennsylvania
Chair of Admissions, Department of Neuroscience MD PhD program, University of Pennsylvania, Perelman School of Medicine
MSTP Program Advisor, University of Pennsylvania
Director for Research Education, Department of Anesthesiology, University of Pennsylvania, Perelman School of Medicine
Member, Committee on Appointments and Promotions, Department of Anesthesiology, University of Pennsylvania
Education Council Member, Children's Hospital of Philadelphia, Department of Anesthesiology
Ombudsman, Department of Anesthesiology and Critical Care, University of Pennsylvania
Department: Anesthesiology and Critical Care

Contact information
3620 Hamilton Walk,
John Morgan Building - Room 334
Philadelphia, PA 19104
Office: 215 573-8208
Fax: 215 349-5078
Lab: 215 898-8929
Graduate Group Affiliations
BS (Molecular Biophysics and Biochemistry)
Yale University, 1993.
MS (Molecular Biophysics and Biochemistry)
Yale University, 1993.
PhD (Neuroscience)
Yale University, 1999.
MD (Medicine)
Yale University, 2000.
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Description of Research Expertise

Molecular Mechanisms of Anesthetic Action
Neurobiology of Sleep Wake Regulation
Mouse Genetics
Molecular Biology
Anesthetic pharmacology

Description of Itmat Expertise

Dr. Kelz studies the systems neuroscience of arousal paying special attention to the neuronal substrates that mediate anesthetic action.

Selected Publications

Mashour GA, Kelz MB: Systems Neuroscience: The Exciting Journey to Oblivion. Current Biology 28(5): R223-4, Mar 2018.

Shortal Brenna P, Reitz Sarah L, Aggarwal Adeeti, Meng Qing C, McKinstry-Wu Andrew R, Kelz Max B, Proekt Alex: Development and validation of brain target controlled infusion of propofol in mice. PLoS one 13(4): e0194949, 2018.

Wasilczuk AZ, Maier KL, Kelz MB: The Mouse as a Model Organism for Assessing Anesthetic Sensitivity. Methods in enzymology 602: 211-228, 2018.

McKinstry-Wu A, Carspecken CW, Proekt A, Kelz MB: Xenon Anesthesia and CT: Noninvasive Measures of Brain Anesthetic Concentration. Methods in enzymology 602: 289-98, 2018.

McKinstry-Wu Andrew R, Kelz Max B: Optoanesthesia: Use of Anesthetic Photolabels In Vivo. Methods in enzymology 603: 171-180, 2018.

Richardson Andrew G, Liu Xilin, Weigand Pauline K, Hudgins Eric D, Stein Joel M, Das Sandhitsu R, Proekt Alexander, Kelz Max B, Zhang Milin, Van der Spiegel Jan, Lucas Timothy H: Hippocampal gamma-slow oscillation coupling in macaques during sedation and sleep. Hippocampus Jul 2017.

Blain-Moraes Stefanie, Tarnal Vijay, Vanini Giancarlo, Bel-Behar Tarik, Janke Ellen, Picton Paul, Golmirzaie Goodarz, Palanca Ben J A, Avidan Michael S, Kelz Max B, Mashour George A: Network Efficiency and Posterior Alpha Patterns Are Markers of Recovery from General Anesthesia: A High-Density Electroencephalography Study in Healthy Volunteers. Frontiers in human neuroscience 11: 328, 2017.

Maier Kaitlyn L, McKinstry-Wu Andrew R, Palanca Ben Julian A, Tarnal Vijay, Blain-Moraes Stefanie, Basner Mathias, Avidan Michael S, Mashour George A, Kelz Max B: Protocol for the Reconstructing Consciousness and Cognition (ReCCognition) Study. Frontiers in human neuroscience 11: 284, 2017.

Wasilczuk AZ, Proekt A, Kelz MB, McKinstry-Wu AR.: High-density Electroencephalographic Acquisition in a Rodent Model Using Low-cost and Open-source Resources. J Vis Exp. 117: e54908, Nov 2016.

Erickson RL, Terzi MC, Jaber SM, Hankenson FC, McKinstry-Wu A, Kelz MB, Marx JO.: Intraperitoneal Continuous-Rate Infusion for the Maintenance of Anesthesia in Laboratory Mice (Mus musculus). J Am Assoc Lab Anim Sci. 55(5): 548-57, September 2016.

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Last updated: 07/26/2018
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