Eric Lancaster

faculty photo
Assistant Professor of Neurology
Department: Neurology

Contact information
3 W. Gates - Neurology
3400 Spruce St.
Philadelphia, PA 19104
Office: 215 898 3575
Fax: 215 349 5579
Lab: 215 898 0181
Graduate Group Affiliations
BS (Biomedical Engineering)
The Johns Hopkins University, 1994.
PhD (Neuroscience)
The University of Maryland, 2002.
MD (medicine)
The University of Maryland, 2003.
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Description of Research Expertise

Neuronal autoantibodies, encephalitis, acquired neuromyotonia (Isaacs' syndrome), peripheral nerve hyperexcitability, potassium channels, the glycine receptor, the GABA-B receptor, neuromuscular disorders, stiff person syndrome.

Description of Itmat Expertise

I am interested in autoimmunity to brain and peripheral nerve proteins. I treat patients with autoimmune disorders in my clinic and try to figure out how their autoimmune diseases work in my lab.

Selected Publications

37. Patterson K, Dalmau J, and Lancaster E. : Mechanisms of Caspr2 antibodies in autoimmune encephalitis and acquired neuromyotonia. Annals of Neurology 83(1): 40-51, Jan 2018.

Burnor E, Yang L, Zhou H, Patterson KR, Quinn C, Reilly MM, Rossor AM, Scherer SS, Lancaster E. : Neurofascin antibodies in autoimmune, genetic and idiopathic neuropathies. Neurology 90(1): e31-38, Jan 2018.

Dhifallah S, Lancaster E, Merrill S, Leroudier N, Mantegazza M, and Cestèle S. : Gain of function for the SCN1A/hNav1.1- L1670W mutation responsible for Familial Hemiplegic Migraine. Frontiers in Molecular Neuroscience. 11: 232, 2018.

Noble G and Lancaster E. : Anti-NMDAR Encephalitis in a Patient with Crohn’s Disease Receiving Adalimumab. Neurology: Neuroimmunology & Neuroinflammation. 5(5): e476. 2018.

Lancaster E.: Paraneoplastic Disorders. Continuum. 23(6): 1653-1679, Dec 2017.

McCracken L, Zhang J, Greene M, Crivaro A, Gonzalez J, Kamoun M, Lancaster E. : Improving the antibody-based evaluation of autoimmune encephalitis. Neurol Neuroimmunol Neuroinflamm. 4(6): e404, Oct 2017.

Lancaster E.: CNS syndromes associated with autoimmunity to metabotropic receptors. Curr Opin Neurol. 30(3): 354-360, Jun 2017.

Greene M, Lai Y, Pajcini K, Bailis W, Pear WS, and Lancaster E. : Delta/Notch-Like EGF-Related Receptor (DNER) Is Not a Notch Ligand. PLoS One. 11(9): e0161157, Sep 2016.

Ariño H, Armangué T, Petit-Pedrol M, Sabater L, Martinez-Hernandez E, Hara M, Lancaster E, Saiz A, Dalmau J, Graus F. : Anti-LGI1-associated cognitive impairment: Presentation and long-term outcome. Neurology 87(8): 759-65, August 2016.

Martinez-Hernandez M, Arino H, McKeon A, Iizuka T, Titulaer M, Simabukuro MM, Lancaster E, Petit-Pedrol M, Planaguma J, Blanco Y, Harvey RJ, Saiz A, Graus F, and Dalmau J. : Clinical and immunological investigations in 121 patients with stiff person spectrum disorder. JAMA Neurology. April 2016 Notes: Epub ahead of print.

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Last updated: 11/14/2018
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