Amy C Durham

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Associate Professor, Anatomic Pathology, University of Pennsylvania School of Veterinary Medicine
Faculty Director, Comparative Pathology Core, School of Veterinary Medicine

Contact information
3950 Delancey Street
Philadelphia, PA 19104
Office: 215 898 7871
Fax: 215 898 0719
BA (Psychology)
University of Virginia, 1997.
MS (Neuroscience)
Georgetown University, 2000.
VMD (Veterinary Medicine)
University of Pennsylvania, 2005.
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Description of Itmat Expertise

Oncologic veterinary pathology
Spontaneous and experimental models of cancer

Description of Research Expertise

Oncologic pathology with a particular interest in lymphoma and employing the World Health Organization classification system for lymphoid neoplasms in domestic animals. One goal of the research is to identify certain subtypes of lymphomas and correlate these subtypes to clinical behavior and optimal treatment protocols. We also hope to gain more insight into these diseases in humans, using the dog as a spontaneous large animal model.

Selected Publications

V.E. Watson, M.M. Hobday, A.C. Durham: Focal intestinal lipogranulomatous lymphangitis: 6 dogs (2008-2011). Journal of Veterinary Internal Medicine 28(1): 48-51, Jan-Feb 2014.

A.C. Durham, A.D. Mariano, E.S. Holmes, L. Aronson: Characterization of post transplantation lymphoma in feline renal transplant recipients. Journal of Comparative Pathology 150(2-3): 162-168, 2014.

A. C. Durham, C. A. Pillitteri, M. San Myint, V. E. Valli: 203 cases of equine lymphoma classified according to the world health organization (WHO) classification criteria. Veterinary Pathology 50(1): 86-93, 2013.

K. E. Flood-Knapik, A. C. Durham,T. P. Gregor, M. D. Sánchez, M. E. Durney, K. U. Sorenmo: Clinical, histopathological and immunohistochemical characterization of canine indolent lymphoma. Veterinary and Comparative Oncology 11(4): 272-286, 2013.

Arielle Glatman Zaretsky, Jonathan S. Silver, Marie Siwicki, Amy Durham, Carl F. Ware, Christopher A. Hunter: Infection with Toxoplasma gondii alters lymphotoxin expression associated with changes in splenic architecture and humoral responses. Infection and Immunity 80(10): 3602-10, Oct 2012.

Avila JL, Troutman S, Durham A, Kissil JL: Notch1 is not required for acinar-to-ductal metaplasia in a model of Kras-induced pancreatic ductal adenocarcinoma. PLoS One 7(12): e52133, 2012.

Elizabeth L. Buza, Robert A. Menzies, Michael H. Goldschmidt, Amy C. Durham: Malignant peripheral nerve sheath tumor in a cat with nodal and pulmonary metastases. Journal of Veterinary Diagnostic Investigation 2012.

Amanda L. Maas, Shirron L. Carter, E. Paul Wileyto, Joann Miller, Min Yuan, Guoqiang Yu, Amy C. Durham, Theresa M. Busch.: Tumor Vascular Microenvironment Determines Responsiveness to Photodynamic Therapy. Cancer Research 72(8): 1-10, 2012.

AC Haley, SR Platt, M Kent, SJ Schatzberg, A Durham, S Cochrane, D Westworth, GD Shelton: Breed specific polymyositis in the Hungarian vizsla dog. Journal of Veterinary Internal Medicine 25(2), 2011.

Eugenia Pacheco-Pinedo, Amy Durham, Kathleen Stewart, Ashley Goss, Min Min Lu, Francesco DeMayo, Edward Morrisey: Wnt/beta-catenin signaling accelerates mouse lung tumorigenesis by imposing an embryonic distal progenitor phenotype on lung epithelium. Journal of Clinical Investigation 121(5): 1935-1945, 2011.

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Last updated: 10/22/2018
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