Richard Aplenc

faculty photo
Associate Professor of Pediatrics at the Children's Hospital of Philadelphia
Associate Physician, The Children's Hospital of Philadelphia
Department: Pediatrics

Contact information
CTRB Room 4018
3501 Civic Center Blvd
Philadelphia, PA 19104
Office: 2674267252
Education:
A.B. (Classics)
Princeton University, 1988.

University of Pennsylvania, Post-Baccalaureate Pre-Health Program, 1989.
MD
University of Virginia, 1994.
MSCE (Clinical Epidemiology and Biostatistics)
University of Pennsylvania, 2002.
PhD (Epidemiology)
University of Pennsylvania, 2011.
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Description of Itmat Expertise

Dr. Aplenc's research involves molecular epidemiology, pediatric cancer Phase I clinical trials, treatment of pediatric AML, and the use of genetic polymorphism data to predict treatment response to therapeutic interventions, particularly in pediatric cancer therapy.

Selected Publications

Miller T. P., Getz K. D., Kavcic M., Li Y., Huang Y. V., Sung L., Alonzo T. A., Gerbing R., Daves M., Horton T. M., Pulsipher M. A., Pollard J., Bagatell R., Seif A. E., Fisher B. T., Gamis A. S., Aplenc R.: A comparison of discharge strategies after chemotherapy completion in pediatric patients with acute myeloid leukemia: A report from the Children's Oncology Group. Leuk Lymphoma Page: 1-8, Jan 2016.

Lee G. E., Fisher B. T., Xiao R., Coffin S. E., Feemster K., Seif A. E., Bagatell R., Li Y., Huang Y. S., Aplenc R.: Burden of influenza-related hospitalizations and attributable mortality in pediatric acute lymphoblastic leukemia. J Pediatric Infect Dis Soc 4(4): 290-6, Dec 2015.

Kutny M.A., Alonzo T.A., Gamazon E.R., Gerbing R.B., Geraghty D., Lange B., Heerema N.A., Sung L., Aplenc R., Franklin J., Raimondi S.C., Hirsch B.A., Konkashbaev A., Cox N.J., Onel K., Gamis A.S., Meshinchi S.: Ethnic variation of TET2 SNP rs2454206 and association with clinical outcome in childhood AML: a report from the Children's Oncology Group. Leukemia 29(12): 2424-6, Dec 2015.

Yu H., Wertheim G., Shankar S., Paessler M., Aplenc R., Pillai V.: Marked eosinophilia masking B lymphoblastic leukemia. Am J Hematol Dec 2015.

Tarlock K., Alonzo T. A., Gerbing R., Raimondi S. C., Hirsch B. A., Sung L., Pollard J. A., Aplenc R., Loken M. R., Gamis A., Meshinchi S.: Gemtuzumab ozogamicin reduces relapse risk in FLT3/ITD acute myeloid leukemia: a report from the Children's Oncology Group. Clin Cancer Res Dec 2015.

Li Y., Hall M., Fisher B. T., Seif A. E., Huang Y. S., Bagatell R., Getz K. D., Alonzo T. A., Gerbing R. B., Sung L., Adamson P. C., Gamis A., Aplenc R.: Merging Children's Oncology Group data with an external administrative database using indirect patient identifiers: A report from the Children's Oncology Group. PLoS One 10(11), Nov 2015.

Getz K. D., Li Y., Alonzo T. A., Hall M., Gerbing R. B., Sung L., Huang Y. S., Arnold S., Seif A. E., Miller T. P., Bagatell R., Fisher B. T., Adamson P. C., Gamis A., Keren R., Aplenc R.: Comparison of in-patient costs for children treated on the AAML0531 clinical trial: a report from the Children’s Oncology Group. Pediatr Blood Cancer 62(10): 1775-81, Oct 2015.

Dix D., Aplenc R., Bowes L., Cellot S., Ethier M. C., Feusner J., Gillmeister B., Johnston D. L., Lewis V., Michon B., Mitchell D., Portwine C., Price V., Silva M., Stobart K., Yanofsky R., Zelcer S., Beyene J., Sung L.: Impact of registration on clinical trials on infection risk in pediatric acute myeloid leukemia. Int J Cancer Oct 2015.

Zwaan C.M., Kolb E.A., Reinhardt D., Abrahamsson J., Adachi S., Aplenc R., De Bont E.S., De Moerloose B., Dworzak M., Gibson B.E., Hasle H., Leverger G., Locatelli F., Ragu C., Ribeiro R.C., Rizzari C., Rubnitz J.E., Smith O.P., Sung L., Tomizawa D., van den Heuvel-Eibrink M.M., Creutzig U., Kaspers G.J.: Collaborative efforts driving progress in pediatric acute myeloid leukemia. J Clin Oncol 33(27): 2949-62, Sept 2015.

Getz K. D., Miller T. P., Seif A. E., Li Y., Huang Y. S., Bagatell R., Fisher B. T., Aplenc R. : A comparison of resource utilization following chemotherapy for acute myeloid leukemia in children discharged versus children that remain hospitalized during neutropenia. Cancer Med 4(9): 1356-64, Sept 2015.

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Last updated: 02/02/2016
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