Manzar Ashtari

faculty photo
Research Associate Professor of Ophthalmology
Director of CNS Imaging, Center for Advanced Retinal and Ocular Therapeutics (CAROT), Department of Ophthalmology, University of Pennsylvania
Department: Ophthalmology
Graduate Group Affiliations

Contact information
Center for Advanced Retinal and Ocular Therapeutics (CAROT)
207A Anatomy-Chemistry Building
3620 Hamilton Walk
Philadelphia, PA 19104
Office: 516-770-3132
Education:
BS (Physics)
Tehran University, Tehran, Iran, 1974.
MS (Nuclear Engineering)
Massachusetts Institute of Technology , 1977.
PhD (Nuclear Engineering)
Massachusetts Institute of Technology , 1982.
Post-Graduate Training
Post Doctoral Fellow, Radiation Therapy, Albert B Chandler Medical Center, University of Kentucky, 1983-1984.
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Description of Itmat Expertise

Application of advanced functional and structural imaging to pediatric and adolescent population. Imaging application to clinical population to identify disease biomarkers.

Selected Publications

Mowad TG, Willett AE, Mahmoudian M, Lipin M, Heinecke A, Maguire AM, Bennett J, Ashtari M: Compensatory Cross-Modal Plasticity Persists After Sight Restoration. Frontiers of Neuroscience May 2020.

Global Surg Collaborative: Global variation in anastomosis and end colostomy formation following left-sided colorectal resection. BJS open 3(3): 403-414, Jun 2019.

Global Surg Collaborative: Pooled analysis of WHO Surgical Safety Checklist use and mortality after emergency laparotomy. The British journal of surgery 106(2): e103-e112, Jan 2019.

Silson EH, Aleman TS, Willett A, Serrano LW, Pearson DJ, Rauschecker AM, Maguire AM, Baker CI, Bennett J, Ashtari M: Comparing Clinical Perimetry and Population Receptive Field Measures in Patients with Choroideremia. Investigative ophthalmology & visual science 59(8): 3249-3258, Jul 2018.

Global Surg Collaborative: Surgical site infection after gastrointestinal surgery in high-income, middle-income, and low-income countries: a prospective, international, multicentre cohort study. The Lancet. Infectious diseases 18(5): 516-525, 05 2018.

Ashtari M, Nikonova ES, Marshall KA, Young GJ, Aravand P, Pan W, Ying GS, Willett AE, Mahmoudian M, Maguire AM, Bennett J: The Role of the Human Visual Cortex in Assessment of the Long-Term Durability of Retinal Gene Therapy in Follow-on RPE65 Clinical Trial Patients. Ophthalmology 124(6): 873-883, Jun 2017.

Betancourt LM, Avants B, Farah MJ, Brodsky NL, Wu J, Ashtari M, Hurt H: Effect of socioeconomic status (SES) disparity on neural development in female African-American infants at age 1 month. Developmental Science 19(6): 947-956, Nov 2016.

Bennett J, Wellman J, Marshall KA, McCague S, Ashtari M, DiStefano-Pappas J, Elci OU, Chung DC, Sun Ji, Wright JF, Cross DR, Aravand P, Cyckowski LL, Bennicelli JL, Mingozzi F, Auricchio A, Pierce EA, Ruggiero J, Leroy BP, Simonelli F, High KA, Maguire AM: Safety and durability of effect of contralateral-eye administration of AAV2 gene therapy in patients with childhood-onset blindness caused by RPE65 mutations: a follow-on phase 1 trial. Lancet (London, England) 388(10045): 661-72, Aug 2016.

Betancourt LM, Avants B, Farah MJ, Brodsky NL, Wu J, Ashtari M, Hurt H : Effect of socioeconomic status (SES) disparity on neural development in female African-American infants at age 1 month. Dev Sci Oct 2015 Notes: Epub ahead of print.

Ashtari M, Zhang H, Cook PA, Cyckowski LL, Shindler KS, Marshall KA, Aravand P, Vossough A, Gee JC, Maguire AM, Baker CI, Bn: Plasticity of the human visual system after retinal gene therapy in patients with Leber's congenital amaurosis. Sci Transl Med 7(296): 296ra110, Jul 2015.

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Last updated: 06/09/2020
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