Frank Milton Balis

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Professor of Pediatrics at the Children's Hospital of Philadelphia
Co-Program Director for Pediatric Oncology, Abramson Cancer Center University of Pennsylvania Philadelphia, PA
Director, Clinical Cancer Research, Center for Childhood Cancer Research The Children's Hospital of Philadelphia Philadelphia, PA
The Louis and Amelia Canuso Family Endowed Chair for Clinical Research in Oncology, The Children's Hospital of Philadelphia Philadelphia, PA
Department: Pediatrics

Contact information
The Children's Hospital of Philadelphia
3501 Civic Center Blvd., Room CTRB4024
Philadelphia, PA 19104
Office: 267-426-5414
Fax: 267-425-5839
B.S. (Zoology)
University of North Carolina, 1971.
M.D. (Medicine)
Vanderbilt University, 1975.
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Description of Itmat Expertise

Drug development for childhood cancers
Clinical pharmacology of anticancer drugs

Description of Other Expertise

Clinical research infrastructure and informatics

Description of Research Expertise

Clinical pharmacology of anticancer drugs, cancer biomarkers, clinical trial design

Selected Publications

Busch C, Reid K, Balis FM, Fox E: Volumetric absorptive microsampling devices (Mitraâ„¢) as a method of sample collection for pharmacokinetic studies in infants. American Society for Mass Spectrometry; Annual Meeting, San Diego, CA June 2018 Notes: Poster presentation.

Frank M. Balis, Christine Busch, Ami Vijay Desai, Emily Hibbitts, Arlene Naranjo, Rochelle Bagatell, Meredith Irwin, Elizabeth Fox: GD2 as a circulating tumor biomarker (CTB) for neuroblastoma (NBL). American Society of Clinical Oncology Annual Meeting, Chicago IL June 2018 Notes: Poster presentation.

Bowen Diana K, Long Christopher J, Balis Frank M, Kolon Thomas F: Case Report: Nephron-sparing Surgery in a Patient With Bilateral Multifocal Wilms Tumor. Urology Apr 2018.

Fox Elizabeth, Levin Kristin, Zhu Yan, Segers Blair, Balamuth Naomi, Womer Richard, Bagatell Rochelle, Balis Frank: Pantoprazole, an Inhibitor of the Organic Cation Transporter 2, Does Not Ameliorate Cisplatin-Related Ototoxicity or Nephrotoxicity in Children and Adolescents with Newly Diagnosed Osteosarcoma Treated with Methotrexate, Doxorubicin, and Cisplatin. The oncologist Feb 2018.

Kraft Ira L, Akshintala Srivandana, Zhu Yuelin, Lei Haiyan, Derse-Anthony Claudia, Dombi Eva, Steinberg Seth M, Lodish Maya, Waguespack Steven G, Kapustina Oxana, Fox Elizabeth, Balis Frank M, Merino Maria J, Meltzer Paul S, Glod John W, Shern Jack F, Widemann Brigitte C: Outcomes of Children and Adolescents with Advanced Hereditary Medullary Thyroid Carcinoma Treated with Vandetanib. Clinical cancer research : an official journal of the American Association for Cancer Research 24(4): 753-765, Feb 2018.

Ramsey Laura B, Balis Frank M, O'Brien Maureen M, Schmiegelow Kjeld, Pauley Jennifer L, Bleyer Archie, Widemann Brigitte C, Askenazi David, Bergeron Sharon, Shirali Anushree, Schwartz Stefan, Vinks Alexander A, Heldrup Jesper: Consensus Guideline for Use of Glucarpidase in Patients with High-Dose Methotrexate Induced Acute Kidney Injury and Delayed Methotrexate Clearance. The oncologist 23(1): 52-61, Jan 2018.

Gore Lia, Ivy S Percy, Balis Frank M, Rubin Eric, Thornton Katherine, Donoghue Martha, Roberts Samantha, Bruinooge Suanna, Ersek Jennifer, Goodman Nancy, Schenkel Caroline, Reaman Gregory: Modernizing Clinical Trial Eligibility: Recommendations of the American Society of Clinical Oncology-Friends of Cancer Research Minimum Age Working Group. Journal of clinical oncology : official journal of the American Society of Clinical Oncology 35(33): 3781-3787, Nov 2017.

Balis FM, Womer RB, Berg S, Winick N, Adamson PC, Fox E: Dosing anticancer drugs in infants: Current approach and recommendations from the Children's Oncology Group's Chemotherapy Standardization Task Force. Pediatr Blood Cancer ePub, May 2017.

Balis FM, Thompson PA, Mosse YP, Blaney SM, Minard CG, Weigel BJ, Fox E: First-dose and steady-state pharmacokinetics of orally administered crizotinib in children with solid tumors: a report on ADVL0912 from the Children's Oncology Group Phase 1/Pilot Consortium. Cancer Chemother Pharmacol 79(1): 181-7, Jan 2017.

Vogel J, Lin H, Both S, Tochner Z, Balis F, Hill-Kayser C.: Pencil beam scanning proton therapy for treatment of the retroperitoneum after nephrectomy for Wilms tumor: A dosimetric comparison study. Pediatr Blood Cancer 64(1): 39-45, Jan 2017.

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Last updated: 05/26/2018
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