William Doyon

faculty photo
Research Assistant Professor of Neuroscience
Department: Neuroscience

Contact information
202A Clinical Research Building
415 Curie Boulevard
Philadelphia, PA 19104
Office: 215-573-1949
BA (Psychology)
New Mexico State University, 1999.
BS (Biology)
New Mexico State University, 1999.
PhD (Pharmacology and Toxicology)
University of Texas, 2005.
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Description of Itmat Expertise

Neurobiology of addiction
Animal models of alcohol abuse
Neurpharmacology of the mesolimbic 'reward' system

Selected Publications

Ostroumov A, Thomas AM, Kimmey BA, Karsch JS, Doyon WM, Dani JA : Stress increases ethanol self-administration via a shift towards excitatory GABA signaling within the ventral tegmental area. Neuron 92: 493-504, October 2016.

Ostroumov A, Thomas AM, Dani JA, Doyon WM : Cigarettes and alcohol: The influence of nicotine on operant alcohol self-administration and the mesolimbic dopamine system. Biochemical Pharmacology. Elsevier, 97(4): 550-557, August 2015.

Doyon William M, Dong Yu, Ostroumov Alexey, Thomas Alyse M, Zhang Tao A, Dani John A : Nicotine Decreases Ethanol-Induced Dopamine Signaling and Increases Self-Administration via Stress Hormones. Neuron 79(3): 530-540, July 2013

Doyon William M, Thomas Alyse M, Ostroumov Alexey, Dong Yu, Dani John A: Potential Substrates for Nicotine and Alcohol Interactions: a Focus on the Mesocorticolimbic Dopamine System. Biochemical Pharmacology 86(8): 1181-1193, July 2013

Li Wei, Doyon William M, Dani John A: Quantitative unit classification of ventral tegmental area neurons in vivo. Journal of Neurophysiology 107(10): 2808-20, May 2012 Notes: CO-FIRST AUTHOR.

Zhang Lifen, Dong Yu, Doyon William M, Dani John A: Withdrawal from chronic nicotine exposure alters dopamine signaling dynamics in the nucleus accumbens. Biological Psychiatry 71(3): 184-91, Feb 2012.

Li Wei, Doyon William M, Dani John A: Acute in vivo nicotine administration enhances synchrony among dopamine neurons. Biochemical Pharmacology 82(8): 977-983, Oct 2011.

Dong Yu, Zhang Tianxiang, Li Wei, Doyon William M, Doyon William, Dani John A: Route of nicotine administration influences in vivo dopamine neuron activity: habituation, needle injection, and cannula infusion. Journal of Molecular Neuroscience: MN 40(1-2): 164-171, Jan 2010.

Zhang Lifen, Doyon William M, Clark Jeremy J, Phillips Paul E M, Dani John A: Controls of tonic and phasic dopamine transmission in the dorsal and ventral striatum. Molecular Pharmacology 76(2): 396-404, Aug 2009.

Doyon William M, Howard Elaina C, Shippenberg Toni S, Gonzales Rueben A: Kappa-opioid receptor modulation of accumbal dopamine concentration during operant ethanol self-administration. Neuropharmacology 51(3): 487-496, Sep 2006.

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Last updated: 09/28/2017
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