Megan S Lim

faculty photo
Professor of Pathology and Laboratory Medicine at the Hospital of the University of Pennsylvania
Director, Division of Hematopathology Joint, Hospital of the University of Pennsylvania and Children’s Hospital of Philadelphia Department of Path and Lab Medicine, University of Pennsylvania
Director, Lymphoma Biology Program, Abramson Cancer Center, University of Pennsylvania (Philadelphia, Pa)
Hematopathologist, Department of Pathology and Laboratory Medicine, Hospital of the University of Pennsylvania, (Philadelphia, PA)
Director, Hematopathology Fellowship Training Program, Department of Pathology and Laboratory Medicine, Hospital of the University of Pennsylvania
Director, Interim, Clinical Flow Cytometry Laboratory, Hospital of the University of Pennsylvania (Philadelphia, PA)
Hematopathologist, Department of Pathology and Laboratory Medicine, Children’s Hospital of Philadelphia, University of Pennsylvania (Philadelphia, PA)
Department: Pathology and Laboratory Medicine

Contact information
Department of Pathology and Laboratory Medicine
Stellar Chance Office Suite 609C
422 Curie Blvd.
Philadelphia, PA 19104
Office: 215-898-4719
Fax: 215-898-9969
BS (Cell and Microbiology)
University of Calgary, 1983.
MS (Biochemistry, Cell Regulation Group, Department of Medical Biochemistry, Faculty of Medicine)
University of Calgary, 1985.
MD (Medicine)
University of Calgary, 1988.
PhD (Molecular Oncology)
University of Calgary joint with National Cancer Institute, National Institute of Health, 1999.
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Description of Itmat Expertise

hematologic cancer
molecular pathogenesis
genomic analysis
mass spectrometry driven proteomics

Selected Publications

Fajgenbaum DC, Oksendhendler E, Casper C, Uldrick, T, Kurzrock R, Yoshizaki K, Nasta S, Rossi JF, Wong R, Simpson D, Sato Y, Terriou L, Ferrero S, Zinzani PL, Hoffman C, Goodman A, Krymskaya V, Elenitoba-Johnson KSJ, Lim MS, Chadburn A, Penmaraju N, Leitch H, Jaffe ES, Jayanthan R, Chandrasakan S, Lechowicz MJ, Ruth J, Greenway A, Stone K, Shilling D, Mukherjee S, Partridge HL, Pierson SK, Streetly M, Schey S, Munshi N, Ide M, Srkalovic G, Fossa A, Dispenzieri A, Voorhees P, van Rhee F.: International, Evidence-based Consensus Treatment Guidelines for the Management of Idiopathic Multicentric Castleman Disease. Blood September 2018.

168. Nam SJ, Kim S, Kwon D, Kim H, Kim S, Lee E, Kim TM, Heo KS, Park SH, Lim MS, Kim CW, Jeon YK.: Prognostic implications of tumor-infiltrating macrophages, M2 macrophages, regulatory T-cells, and indoleamine 2,3-dioxygenase-positive cells in primary diffuse large B-cell lymphoma of the central nervous system. Oncoimmunology. Taylor & Francis Online (eds.). 13(7), May 2018.

Bhatti M, Ippolito T, Mavis C, Gu J, Cairo MS, Lim MS, Hernandez-Ilizaliturri F, Barth MJ: Pre-clinical activity of targeting the PI3K/Akt/m TOR pathway in Burkitt lymphoma. Oncotarget. Andei V. Gudkov, Mikhail V. Blagosklonny (eds.). Impact Journals, 9(31): 21820-21830, April 2018.

Van Arnam JS, Lim MS, Elenitoba-Johnson KSJ: Novel Insights into the pathogenesis of T-cell Lymphomas. Blood. Bob Löwenberg, MD, PhD (eds.). 11, April 2018.

Prokoph N, Larose H, Lim MS, Burke GAA, Turner SD.: Treatment Options for Paediatric Anaplastic Large Cell Lymphoma (ALCL): Current Standard and beyond. Cancers (Basel). MDPI (eds.). 10(4), Mar 2018.

Wu D, Lim MS, Jaffe ES. : Pathology of Castleman Disease. Hematol Oncol Clin North Am 32(1): 37-52, Feb 2018.

Udager AM, McHugh JB, Goudsmit CM, Weigelin HC, Lim MS, Elenitoba-Johnson KSJ, Betz BL, Carey TE, Brown NA.: Human Papillomavirus (HPV) and somatic EGFR mutations are essential, mutually exclusive oncogenic mechanisms for inverted sinonasal papillomas and associated sinonasal squamous cell carcinomas. Annals of Oncol. Nov 2017.

Elenitoba-Johnson KSJ, Lim MS: New Insights into Lymphoma Pathogenesis. Annu Rev Pathol Nov 2017.

Mosse YP, Voss SD, Lim MS, Rolland DCM, Minard CG, Fox E, Adamson PC, Wilner K, Blaney SM, Weigel B.: Targeting ALK with Cizotinib in Pediatric Anaplastic Large Cell Lymphoma and Inflammatory Myofibroblastic Tumor: A Children's Oncology Group Study. J Clin Oncol 35(28): 3215-3221, Oct 2017.

Önder Ö, Rolland DCM, Yuan Z-F, Garcia BA, Lim MS and Elenitoba-Johnson KSJ: Poster presentation "Characterization of Histone Post-Translational Modifications of Cutaneous T-cell Lymphomas" 65thAmerican Society for Mass Spectrometry Conference on Mass Spectrometry & Allied Topics June 2017.

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Last updated: 10/25/2018
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