Ivan S. Alferiev

faculty photo
Research Associate Professor of Pediatrics
Department: Pediatrics

Contact information
Abramson Pediatric Research Center, Room 702
The Children's Hospital of Philadelphia
34th & Civic Center Blvd.
Philadelphia, PA 19104
Office: 2155902228
Education:
M.S. (Chemistry)
Novosibirsk State University, Novosibirsk, USSR, 1968.
Ph.D. (Chemistry)
Novosibirsk State University, USSR, work done at the Institute of Chemical Kinetics and Combustion, 1978.
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Description of Itmat Expertise

chemical approaches for drug and biomaterials modification; prodrug and codrug synthesis

Selected Publications

Alferiev, I.S., Fishbein, I.: Activated polyurethane modified with latent thiol groups. Biomaterials 23(24): 4753-4758, Dec 2002.

Alferiev, I.S.: Novel elastomeric polyurethanes with pendant epoxy groups as highly reactive auxiliary groups for further derivatizations. Journal of Polmer Science: Part A: Polymer Chemistry 40: 4378-4385, 2002.

Alferiev, I.S., Stachelek, S.J., Song, C., Connolly, M., Bianco, R.W., Levy, R.J.: Gene delivery from polyurethane heart valve cusps and vascular implants. 28th Annual meeting of the Society for Biomaterials. Tampa Florida(518), 2002.

Alferiev, I.S., Vyavahare, N.R., Song, C.X., Levy, R.J.: Elastomeric polyurethanes modified with geminal bisphosphonate groups. Journal of Polymer Science: Part A: Polymer Chemistry 39: 105-116, 2001.

Alferiev, I.S., Hinson, J.T., Ogle, M., Breuer, E., Levy, R.J.: High reactivity of alkyl sulfides towards epoxides under conditions of collagen fixation - a convenient approach to 2-amino-4-butyrolactones. Biomaterials 22: 2501-2506, 2001.

Alferiev, I.S., Vyavahare, N.R., Song, C.X., Connoly, J., Hinson J.T. Lu, Zh.B., Tallapragada, S., Bianco, R., Levy, R.J.: Bisphosphonate derivatized polyurethanes resist calcificaton. Biomaterials 22: 2683-2693, 2001.

Ezra, A., Hoffman, A., Breuer, E., Alferiev, I.S., Mönkönen, El Hanany-Rozen, N., Weiss, G., Stepinsky, D., Gati, I., Cohen, H., Törmälehto, Amidon, G.L., Golomb, G.: A peptide prodrug approach for improving bisphosphonate oral absorption. Journal of Medicinal Chemistry 43(20): 3641-3652, Oct 2000.

Vyavahare, N.R., Alferiev, I.S., Levy, R.J.: Bisphosphonate modified polyurethanes resist calcification. Society for Biomaterials Proceedings. Hawaii 1111, May 2000.

Martin, V.V., Alferiev, I.S., Weis, A.L.: Amplified fluorescent molecular probes based on 1,3,5,7-tetrasubstituted adamantane. Tetrahedron Letters 40(2): 223-226, 1999.

Weis, A.L., Bakos,T., Alferiev, I.S., Zhang, X., Shao, B., Kinney, W.A.: Synthesis of an azido spermidine equivalent. Tetrahedron Letters 40(26): 4863-4864, 1999.

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Last updated: 11/19/2017
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