Giorgio Sirugo

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Contact information
Ospedale San Pietro
Via Cassia 600
Rome, 00189
Education:
MD (Medicine and Surgery)
University of Pavia, 1987.
PhD (Molecular Biology )
Louis Pasteur University, 1991.
Post-Graduate Training
Postdoctoral Studies Human Genetics, Yale University, 1992-1998.
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Selected Publications

Zetola NM, Modongo C, Mathlagela K, Sepako E, Matsiri O, Tamuhla T, Mbongwe B, Martinelli E, Sirugo G, Paolesse R, Di Natale C: Identification of a Large Pool of Microorganisms with an Array of Porphyrin Based Gas Sensors. Sensors 16(4): E466, Apr 2016.

Sobota RS, Stein CM, Kodaman N, Scheinfeldt LB, Maro I, Wieland-Alter W, Igo RP Jr, Magohe A, Malone LL, Chervenak K, Hall NB, Modongo C, Zetola N, Matee M, Joloba M, Froment A, Nyambo TB, Moore JH, Scott WK, Lahey T, Boom WH, von Reyn CF, Tishkoff SA, Sirugo G, Williams SM: A Locus at 5q33.3 Confers Resistance to Tuberculosis in Highly Susceptible Individuals. Am J Hum Genet 98(3): 514-524, Mar 2016.

Modongo C, Pasipanodya JG, Zetola NM, Williams SM, Sirugo G, Gumbo T: Amikacin Concentrations Predictive of Ototoxicity in Multidrug-Resistant Tuberculosis Patients. Antimicrob Agents Chemother 59(10): 6337-6343, Oct 2015.

Malaria Genomic Epidemiology Network: Reappraisal of known malaria resistance loci in a large multi center study. Nat Genet 46(11): 1197-1204, Nov 2014.

Modongo C, Sobota RS, Kesenogile B, Ncube R, Sirugo G, Williams SM, Zetola NM: Successful MDR-TB treatment regimens including amikacin are associated with high rates of hearing loss. BMC Infect Dis 14: 542, Oct 2014.

White MJ, Tacconelli A, Chen JS, Wejse C, Hill PC, Gomes VF, Velez-Edwards DR, Ƙstergaard LJ, Hu T, Moore JH, Novelli G, Scott WK, Williams SM, Sirugo G: Epiregulin (EREG) and human V-ATPase (TCIRG1): genetic variation, ethnicity and pulmonary tuberculosis susceptibility in Guinea-Bissau and The Gambia. Genes Immun 15(6): 370-377, Sep 2014.

Sirugo G, Predazzi IM, Bartlett J, Tacconelli A, Walther M, Williams SM: G6PD A- deficiency and severe malaria in The Gambia: heterozygote advantage and possible homozygote disadvantage. Am J Trop Med Hyg 90(5): 856-859, May 2014.

Hu T, Chen Y, Kiralis JW, Collins RL, Wejse C, Sirugo G, Williams SM, Moore JH: An information-gain approach to detecting three-way epistatic interactions in genetic association studies. J Am Med Inform Assoc 20(4): 630-636, Jul-Aug 2013.

Predazzi IM, Rokas A, Deinard A, Schnetz-Boutaud N, Williams ND, Bush WS, Tacconelli A, Friedrich K, Fazio S, Novelli G, Haines JL, Sirugo G, Williams SM: Putting pleiotropy and selection into context defines a new paradigm for interpreting genetic data. Circ Cardiovasc Genet 6(3): 299-307, Jun 2013.

Band G, Le QS, Jostins L, Pirinen M, Kivinen K, Jallow M, Sisay-Joof F, Bojang K, Pinder M, Sirugo G, Conway DJ, Nyirongo V, Kachala D, Molyneux M, Taylor T, Ndila C, Peshu N, Marsh K, Williams TN, Alcock D, Andrews R, Edkins S, Gray E, Hubbart C, Jeffreys A, Rowlands K, Schuldt K, Clark TG, Small KS, Teo YY, Kwiatkowski DP, Rockett KA, Barrett JC, Spencer CC; Malaria Genomic Epidemiology Network: Imputation-based meta-analysis of severe malaria in three African populations. PLoS Genet 9(6): e1003509, May 2013.

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Last updated: 09/17/2019
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