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Denys V. Volgin, Ph.D.

Contact information
Department of Animal Biology, University of Pennsylvania
Philadelphia, PA 19104
Ph.D. (Biological Sciences/Physiology)
Bogomoletz Institute of Physiology (Natl. Acad. Sci. of Ukraine) , 1999.
Post-Graduate Training
Postdoctoral Training (Molecular Neuropharmacology), Department of Animal Biology, University of Pennsylvania, 1999-2002.
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Description of Research Expertise

- Role of arginylation in the function of intracellular protein targets (with focus on cytoskeleton, cell motility, and signaling)
- Molecular and cellular mechanisms of neurobehavioral developmental disorders
- Molecular neuropharmacology of sleep and sleep-related respiratory disorders (obstructive sleep apnea)
- Central control of breathing and its postnatal development
- Molecular and cellular mechanisms of hypoxia.

Selected Publications

Cornachione AS, Leite FS, Wang J, Leu NA, Kalganov A, Volgin D, Han X, Xu T, Cheng YS, Yates JR 3rd, Rassier DE, Kashina A.: Arginylation of myosin heavy chain regulates skeletal muscle strength. Cell Rep. Page: pii: S2211-1247(14)00487-2. 2014.

Volgin DV, Lu JW, Stettner GM, Mann GL, Ross RJ, Morrison AR, Kubin L.: Time- and behavioral state-dependent changes in posterior hypothalamic GABAA receptors contribute to the regulation of sleep PLoS ONE 9(1): e86545, 2014.

Stettner GM, Kubin L, Volgin DV: Loss of motoneurons in the ventral compartment of the rat hypoglossal nucleus following early postnatal exposure to alcohol. Journal of Chemical Neuroanatomy 52: 87-94, 2013.

Volgin DV, Stettner GM, Kubin L: Circadian dependence of receptors that mediate wake-related excitatory drive to hypoglossal motoneurons. Respiratory Physiology & Neurobiology 188: 301-307, 2013.

Volgin DV, Kubin L: Reduced sleep and impaired sleep initiation in adult male rats exposed to alcohol during early postnatal period. Behavioural Brain Research 2012 Notes: http://dx.doi.org/10.1016/j.bbr.2012.06.002.

Stettner GM, Kubin L, Volgin DV: Antagonism of orexin 1 receptors eliminates motor hyperactivity and improves homing response acquisition in juvenile rats exposed to alcohol during early postnatal period. Behavioural Brain Research 221(1): 324-8, 2011.

Volgin DV, Malinowska M, Kubin L: Dorsomedial pontine neurons with descending projections to the medullary reticular formation express orexin-1 and adrenergic alpha2A receptor mRNA. Neuroscience Letters 459(3): 115-8, 2009.

Volgin DV, Rukhadze I Kubin L: Hypoglossal premotor neurons of the intermediate medullary reticular region express cholinergic markers. Journal of Applied Physiology 105(5): 1576-84, 2008.

Kubin L, Volgin DV: Developmental profiles of neurotransmitter receptors in respiratory motor nuclei. Respiratory Physiology & Neurobiology 164(1-2): 64-71, 2008.

Volgin DV, Kubin L: Regionally selective effects of GABA on hypothalamic GABAA receptor mRNA in vitro. Biochemical and Biophysical Research Communications 353(3): 726-32, 2007.

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Last updated: 03/10/2015
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