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Anil K. Rustgi, MD

Emeritus Professor of Medicine
Department: Medicine

Contact information
Columbia University Vagelos College of Physicians and Surgeons
630 West 168th Street
New York, NY 10032
BS (Molecular Biochemistry & Biophysics)
Yale University, New Haven, CT, 1980.
MD (Medicine)
Duke University, Durham, NC, 1984.
Post-Graduate Training
Medical Internship, Beth Israel Hospital/Harvard Medical School, 1984-1985.
Medical Resident, Beth Israel Hospital/Harvard Medical School, 1985-1987.
Chief Medical Resident, Beth Israel Hospital/Brockton VA, Harvard Medical School , 1987-1987.
Clinical and Research Fellow in Gastroenterology, Massachusetts General Hospital, Harvard Medical School, 1987-1990.
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Description of Research Expertise

Oncogenes, tumor suppressor genes, tumor microenvironment, tumor metastasis, molecular genetics of GI cancers (colon, pancreatic, upper GI)

Description of Other Expertise

Our laboratory has had long-standing thematic interests in the cell-type and tissue-type specific actions of certain oncogenes (cyclin D1, EGFR) and tumor suppressor genes (p53, p120 catenin) in modulating the initiation, progression and invasion of gastrointestinal cancers, especially upper GI, pancreatic and colon. To that end, we employ novel three-dimensional cell culture systems (mouse and human origins) and genetically-engineered mouse models to investigate molecular mechanisms. These projects are translated into the objectives of improving molecular diagnostics and experimental therapeutics in patients.
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Last updated: 07/27/2020
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