Penn Medicine's brainSTIM Center seeks to be a preeminent center for supporting scientific research and the development of clinical interventions that employ neuromodulation.

The center uses a range of neuromodulation tools, including transcranial magnetic stimulation (TMS), and transcranial electrical stimulation (tES) techniques such as transcranial direct current stimulation (tDCS), and transcranial alternating current stimulation (tACS). We combine these technologies with tools that elucidate brain structures and functions, such as structural and functional magnetic resonance imaging (MRI) electroencephalography (EEG), electromyography (EMG). Combining technologies that characterize the brain with tools that allow us to manipulate the brain allows us to explore key structure-function relationships that underlie human cognition and neural function, and to explore clinical applications of neuromodulation for patients with a wide range of brain disorders.