Publications

1. Pal AA#, Benman W#, Mumford TR, Chow BY, Bugaj LJ*. (2023) Optogenetic clustering and membrane translocation of the BcLOV4 photoreceptor. Proceed Nat Acad Sci USA. August 1, 2023. doi: 10.1073/pnas.2221615120
2. Benman W, Berlew EE, Deng H, Parker C, Kuznetsov I, Lim B, Siekmann A, Chow BY, Bugaj LJ*. (2022). Temperature-responsive optogenetic probes of cell signaling. Nature Chemical Biology. doi: 10.1038/s41589-021-00917-0
3. Rosenbloom AB, Tarczyński M, Lam N, Kane RS*, Bugaj LJ*, Schaffer DV*. (2020). β-Catenin signaling dynamics regulate cell fate in differentiating neural stem cells. Proceed Nat Acad Sci USA. 117 (46) 28828-28837.
4. Mumford TR, Roth L, Bugaj LJ*. (2020) Reverse and Forward Engineering Multicellular Structures with Optogenetics. Current Opinion in Biomedical Engineering. doi: 10.1016/j.cobme.2020.100250.
5. Bugaj LJ*, Lim W.A. (2019). High-throughput multiplexed optogenetics in microwell plates. Nature Protocols. 14(7):2205-2228
6. Bugaj LJ, Sabnis, A.J., Mitchell, A., Garbarino, J.E., Toettcher, J.E.*, Bivona, T.G.*, and Lim, W.A.* (2018). Cancer mutations and targeted drugs can disrupt dynamic signal encoding by the Ras-Erk pathway. Science. 361.
7. Bugaj LJ, O’Donoghue GP, Lim WA*. (2016) Interrogating Cellular Perception and Decision Making with Optogenetic Tools. J Cell Biol. Dec 21.
8. Bugaj LJ, Mesuda CK, Varedi M, Kane RS*, Schaffer DV*. (2015) Regulation of endogenous transmembrane receptors through optogenetic Cry2 clustering. Nature Communications. 6, Article 6898.
9. Bugaj LJ, Choksi AT, Mesuda CK, Kane RS*, Schaffer DV*. (2013). Optogenetic protein clustering and signaling activation in mammalian cells. Nature Methods. 10(3), 249-25.