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Ellebrecht Lab

Publications

 

  1. Wat M, Mollanazar NK, Ellebrecht CT, Forrestel A, Elenitsas R, Chu EY. Lichen planus pemphigoides-like reaction to PD-1 checkpoint blockade. J Cutan Pathol. 2022 Aug 3;. doi: 10.1111/cup.14299. [Epub ahead of print] PubMed PMID: 36054729.
  2. Ellebrecht CT, Maseda D, Payne AS. Pemphigus and Pemphigoid: From Disease Mechanisms to Druggable Pathways. J Invest Dermatol. 2022 Mar;142(3 Pt B):907-914. doi: 10.1016/j.jid.2021.04.040. Epub 2021 Oct 29. Review. PubMed PMID: 34756581; PubMed Central PMCID: PMC8860856.
  3. Niebuhr M, Belde J, Fähnrich A, Serge A, Irla M, Ellebrecht CT, Hammers CM, Bieber K, Westermann J, Kalies K. Receptor repertoires of murine follicular T helper cells reveal a high clonal overlap in separate lymph nodes in autoimmunity. Elife. 2021 Aug 17;10. doi: 10.7554/eLife.70053. PubMed PMID: 34402793; PubMed Central PMCID: PMC8370764.
  4. Godse R, Mcgettigan S, Schuchter LM, Ellebrecht CT, Chu EY. Vogt-Koyanagi-Harada-like syndrome in the setting of combined anti-PD1/anti-CTLA4 therapy. Clin Exp Dermatol. 2021 Aug;46(6):1111-1112. doi: 10.1111/ced.14640. Epub 2021 Apr 13. PubMed PMID: 33846999.
  5. Gelfand JM, Armstrong AW, Bell S, Anesi GL, Blauvelt A, Calabrese C, Dommasch ED, Feldman SR, Gladman D, Kircik L, Lebwohl M, Lo Re V 3rd, Martin G, Merola JF, Scher JU, Schwartzman S, Treat JR, Van Voorhees AS, Ellebrecht CT, Fenner J, Ocon A, Syed MN, Weinstein EJ, Gondo G, Heydon S, Koons S, Ritchlin CT. National Psoriasis Foundation COVID-19 Task Force guidance for management of psoriatic disease during the pandemic: Version 2-Advances in psoriatic disease management, COVID-19 vaccines, and COVID-19 treatments. J Am Acad Dermatol. 2021 May;84(5):1254-1268. doi: 10.1016/j.jaad.2020.12.058. Epub 2021 Jan 7. PubMed PMID: 33422626; PubMed Central PMCID: PMC7788316.
  6. Gelfand JM, Armstrong AW, Bell S, Anesi GL, Blauvelt A, Calabrese C, Dommasch ED, Feldman SR, Gladman D, Kircik L, Lebwohl M, Lo Re V 3rd, Martin G, Merola JF, Scher JU, Schwartzman S, Treat JR, Van Voorhees AS, Ellebrecht CT, Fenner J, Ocon A, Syed MN, Weinstein EJ, Smith J, Gondo G, Heydon S, Koons S, Ritchlin CT. National Psoriasis Foundation COVID-19 Task Force Guidance for Management of Psoriatic Disease During the Pandemic: Version 1. J Am Acad Dermatol. 2020 Dec;83(6):1704-1716. doi: 10.1016/j.jaad.2020.09.001. Epub 2020 Sep 4. PubMed PMID: 32891785; PubMed Central PMCID: PMC7471802.
  7. Lee J, Lundgren DK, Mao X, Manfredo-Vieira S, Nunez-Cruz S, Williams EF, Assenmacher CA, Radaelli E, Oh S, Wang B, Ellebrecht CT, Fraietta JA, Milone MC, Payne AS. Antigen-specific B cell depletion for precision therapy of mucosal pemphigus vulgaris. J Clin Invest. 2020 Dec 1;130(12):6317-6324. doi: 10.1172/JCI138416. PubMed PMID: 32817591; PubMed Central PMCID: PMC7685721.
  8. Ellebrecht CT, Lundgren DK, Payne AS. On the mark: genetically engineered immunotherapies for autoimmunity. Curr Opin Immunol. 2019 Dec;61:69-73. doi: 10.1016/j.coi.2019.08.005. Epub 2019 Sep 26. Review. PubMed PMID: 31563849; PubMed Central PMCID: PMC6901707.
  9. Ellebrecht CT, Mukherjee EM, Zheng Q, Choi EJ, Reddy SG, Mao X, Payne AS. Autoreactive IgG and IgA B Cells Evolve through Distinct Subclass Switch Pathways in the Autoimmune Disease Pemphigus Vulgaris. Cell Rep. 2018 Aug 28;24(9):2370-2380. doi: 10.1016/j.celrep.2018.07.093. PubMed PMID: 30157430; PubMed Central PMCID: PMC6156788.
  10. Payne AS, Kasperkiewicz M, Ellebrecht CT, Takahashi H, Yamagami J, Zillikens D, Amagai M. Correction: Paraneoplastic autoimmune multiorgan syndrome and paraneoplastic pemphigus describe the same spectrum of disease pathology. Nat Rev Dis Primers. 2018 May 11;4:18032. doi: 10.1038/nrdp.2018.32. PubMed PMID: 29749393.
  11. Payne AS, Kasperkiewicz M, Ellebrecht CT, Takahashi H, Yamagami J, Zillikens D, Amagai M. Authors' reply: Paraneoplastic autoimmune multi-organ syndrome is a distinct entity from traditional pemphigus subtypes. Nat Rev Dis Primers. 2018 Feb 22;4:18013. doi: 10.1038/nrdp.2018.13. PubMed PMID: 29469088.
  12. Leibman RS, Richardson MW, Ellebrecht CT, Maldini CR, Glover JA, Secreto AJ, Kulikovskaya I, Lacey SF, Akkina SR, Yi Y, Shaheen F, Wang J, Dufendach KA, Holmes MC, Collman RG, Payne AS, Riley JL. Supraphysiologic control over HIV-1 replication mediated by CD8 T cells expressing a re-engineered CD4-based chimeric antigen receptor. PLoS Pathog. 2017 Oct;13(10):e1006613. doi: 10.1371/journal.ppat.1006613. eCollection 2017 Oct. PubMed PMID: 29023549; PubMed Central PMCID: PMC5638568.
  13. Kasperkiewicz M, Ellebrecht CT, Takahashi H, Yamagami J, Zillikens D, Payne AS, Amagai M. Pemphigus. Nat Rev Dis Primers. 2017 May 11;3:17026. doi: 10.1038/nrdp.2017.26. Review. PubMed PMID: 28492232; PubMed Central PMCID: PMC5901732.
  14. Mao X, Cho MJT, Ellebrecht CT, Mukherjee EM, Payne AS. Stat3 regulates desmoglein 3 transcription in epithelial keratinocytes. JCI Insight. 2017 May 4;2(9). doi: 10.1172/jci.insight.92253. eCollection 2017 May 4. PubMed PMID: 28469076; PubMed Central PMCID: PMC5414550.
  15. Ellebrecht CT, Payne AS. Setting the target for pemphigus vulgaris therapy. JCI Insight. 2017 Mar 9;2(5):e92021. doi: 10.1172/jci.insight.92021. Review. PubMed PMID: 28289723; PubMed Central PMCID: PMC5333961.
  16. Chen J, Zheng Q, Hammers CM, Ellebrecht CT, Mukherjee EM, Tang HY, Lin C, Yuan H, Pan M, Langenhan J, Komorowski L, Siegel DL, Payne AS, Stanley JR. Proteomic Analysis of Pemphigus Autoantibodies Indicates a Larger, More Diverse, and More Dynamic Repertoire than Determined by B Cell Genetics. Cell Rep. 2017 Jan 3;18(1):237-247. doi: 10.1016/j.celrep.2016.12.013. PubMed PMID: 28052253; PubMed Central PMCID: PMC5221611.
  17. Cho MJ, Ellebrecht CT, Hammers CM, Mukherjee EM, Sapparapu G, Boudreaux CE, McDonald SM, Crowe JE Jr, Payne AS. Determinants of VH1-46 Cross-Reactivity to Pemphigus Vulgaris Autoantigen Desmoglein 3 and Rotavirus Antigen VP6. J Immunol. 2016 Aug 15;197(4):1065-73. doi: 10.4049/jimmunol.1600567. Epub 2016 Jul 11. PubMed PMID: 27402694; PubMed Central PMCID: PMC4976025.
  18. Bhoj VG, Arhontoulis D, Wertheim G, Capobianchi J, Callahan CA, Ellebrecht CT, Obstfeld AE, Lacey SF, Melenhorst JJ, Nazimuddin F, Hwang WT, Maude SL, Wasik MA, Bagg A, Schuster S, Feldman MD, Porter DL, Grupp SA, June CH, Milone MC. Persistence of long-lived plasma cells and humoral immunity in individuals responding to CD19-directed CAR T-cell therapy. Blood. 2016 Jul 21;128(3):360-70. doi: 10.1182/blood-2016-01-694356. Epub 2016 May 10. PubMed PMID: 27166358; PubMed Central PMCID: PMC4957161.
  19. Ellebrecht CT, Bhoj VG, Nace A, Choi EJ, Mao X, Cho MJ, Di Zenzo G, Lanzavecchia A, Seykora JT, Cotsarelis G, Milone MC, Payne AS. Reengineering chimeric antigen receptor T cells for targeted therapy of autoimmune disease. Science. 2016 Jul 8;353(6295):179-84. doi: 10.1126/science.aaf6756. Epub 2016 Jun 30. PubMed PMID: 27365313; PubMed Central PMCID: PMC5343513.
  20. Lo AS, Mao X, Mukherjee EM, Ellebrecht CT, Yu X, Posner MR, Payne AS, Cavacini LA. Pathogenicity and Epitope Characteristics Do Not Differ in IgG Subclass-Switched Anti-Desmoglein 3 IgG1 and IgG4 Autoantibodies in Pemphigus Vulgaris. PLoS One. 2016;11(6):e0156800. doi: 10.1371/journal.pone.0156800. eCollection 2016. PubMed PMID: 27304671; PubMed Central PMCID: PMC4909199.
  21. Ellebrecht CT, Srinivas G, Bieber K, Banczyk D, Kalies K, Künzel S, Hammers CM, Baines JF, Zillikens D, Ludwig RJ, Westermann J. Skin microbiota-associated inflammation precedes autoantibody induced tissue damage in experimental epidermolysis bullosa acquisita. J Autoimmun. 2016 Apr;68:14-22. doi: 10.1016/j.jaut.2015.08.007. Epub 2015 Sep 1. PubMed PMID: 26341384.
  22. Ellebrecht DB, Wolken H, Ellebrecht CT, Bruch HP, Kleemann M. [Positioning Injuries to Peripheral Nerves during Laparoscopic Colon and Rectum Surgery]. Zentralbl Chir. 2015 Dec;140(6):610-6. doi: 10.1055/s-0032-1328178. Epub 2013 Jul 3. PubMed PMID: 23824613.
  23. Cho MJ, Ellebrecht CT, Payne AS. The dual nature of interleukin-10 in pemphigus vulgaris. Cytokine. 2015 Jun;73(2):335-41. doi: 10.1016/j.cyto.2014.11.002. Epub 2014 Nov 22. Review. PubMed PMID: 25464924; PubMed Central PMCID: PMC4437817.
  24. Ellebrecht CT, Choi EJ, Allman DM, Tsai DE, Wegener WA, Goldenberg DM, Payne AS. Subcutaneous veltuzumab, a humanized anti-CD20 antibody, in the treatment of refractory pemphigus vulgaris. JAMA Dermatol. 2014 Dec;150(12):1331-5. doi: 10.1001/jamadermatol.2014.1939. PubMed PMID: 25133328; PubMed Central PMCID: PMC5897695.
  25. Cho MJ, Lo AS, Mao X, Nagler AR, Ellebrecht CT, Mukherjee EM, Hammers CM, Choi EJ, Sharma PM, Uduman M, Li H, Rux AH, Farber SA, Rubin CB, Kleinstein SH, Sachais BS, Posner MR, Cavacini LA, Payne AS. Shared VH1-46 gene usage by pemphigus vulgaris autoantibodies indicates common humoral immune responses among patients. Nat Commun. 2014 Jun 19;5:4167. doi: 10.1038/ncomms5167. PubMed PMID: 24942562; PubMed Central PMCID: PMC4120239.
  26. Ellebrecht CT, Payne AS. Plakophilins, desmogleins, and pemphigus: the tail wagging the dog. J Invest Dermatol. 2014 Apr;134(4):874-876. doi: 10.1038/jid.2013.491. PubMed PMID: 24646797; PubMed Central PMCID: PMC3968779.
  27. Funakoshi T, Lunardon L, Ellebrecht CT, Nagler AR, O'Leary CE, Payne AS. Enrichment of total serum IgG4 in patients with pemphigus. Br J Dermatol. 2012 Dec;167(6):1245-53. doi: 10.1111/j.1365-2133.2012.11144.x. Epub 2012 Sep 27. PubMed PMID: 22803659; PubMed Central PMCID: PMC3601918.
  28. Hammers CM, Bieber K, Kalies K, Banczyk D, Ellebrecht CT, Ibrahim SM, Zillikens D, Ludwig RJ, Westermann J. Complement-fixing anti-type VII collagen antibodies are induced in Th1-polarized lymph nodes of epidermolysis bullosa acquisita-susceptible mice. J Immunol. 2011 Nov 15;187(10):5043-50. doi: 10.4049/jimmunol.1100796. Epub 2011 Oct 3. PubMed PMID: 21967893.

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