Research

At Ma lab for Immune Engineering, we employ a combination of genetic, chemistry, engineering and computational tools to decode the molecular and cellular crosstalk between immune cells and their microenvironment, and leverage these crosstalk mechanisms to engineer novel biomaterials, protein, and cell-based precision immunotherapies.

 1) Chemical and biomaterials engineering to dissect and manipulate immune cell-cell and cell-tissue crosstalk to enhance cellular therapy and promote vaccine development,

2) Genetic engineering and synthetic immunology to create intelligent cells that integrate environmental cues for decision making,

3) Protein engineering to develop safe and potent immune-modulatory proteins and nanostructures with desired trafficking profile, release kinetics, enhanced or novel functions.