Don L. Siegel, PhD, MD

Professor, Pathology & Laboratory Medicine
Founding Director, Division of Transfusion Medicine & Therapeutic Pathology
Director, Clinical Cell & Vaccine Production Facility, Center for Advanced Cellular Therapeutics

Dr. Siegel received an undergraduate degree in Biophysics from Brown University, a Ph.D. in Biophysics from Harvard University, and an M.D. from the University of Pennsylvania.  He completed a residency in Clinical Pathology and Fellowship in Blood Banking/Transfusion Medicine at the Hospital of the University of Pennsylvania before joining Penn as a member of the faculty in 1992.

At the Hospital of the University of Pennsylvania, Dr. Siegel is the Founding Director of the Division of Transfusion Medicine & Therapeutic Pathology which comprises the hospital blood bank/transfusion service, apheresis/cell infusion unit, and hematopoietic stem cell laboratory.  Within the University, Dr. Siegel currently serves as Director of the Clinical Cell and Vaccine Production facility, a FACT-accredited, GMP resource within the Center for Cellular Immunotherapies.

Since 2017, Dr. Siegel has been recognized with the RISE Award, the Dale E. Smith Memorial Award, the Tibor Greenwalt Memorial Award and Lectureship, the Emily Cooley Memorial Award and Lectureship, and election to the NBF Hall of Fame from the Association for the Advancement of Blood and Biotherapies, and the Francis S. Morrison Award and the Lecturer Award from American Society for Apheresis. For contributions to the development of CAR T-cell therapy, Dr. Siegel shared the 2020 Robert de Villiers Spiral of Life Award from the Leukemia Lymphoma Society and the 2020 Society for the immunotherapy of Cancer Team Science Award.