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Silverbush Lab

Publications

*equal contribution  #corresponding author

  1. Freeburg NF*, Chafamo D*, … Silverbush D#. “The critical role of the host endogenous immune compartment after intracerebroventricular CAR T cell therapy in recurrent GBM”, In review.
  2. Silverbush D#, … Suvà M#, Hovestadt V#. “Towards an integrated cellular and molecular classifier for glioblastoma”, In review.
  3. Bagley S, Desai A, Fraietta J, Silverbush D, …, O’Rourke D#. “Intracerebroventricular bivalent CAR T cells targeting EGFR and IL-13Rα2 in recurrent glioblastoma: a phase 1 trial”, Nature Medicine, 2025, PMID: 40451950.
  4. Silverbush D. “Rethinking Tumor Purity Estimation in the Era of AI”, Neuro-Oncology, Editorial, 2025, PMID: 40168178.
  5. Silverbush D, Suvà M*, Hovestadt V*. “Inferring glioblastoma cell type and cell state composition from bulk DNA methylation profiles using multi-omic single-cell analyses”, abstract accepted for oral presentation at Society of Neuro Oncology, Annual Meeting, 2022, link.
  6. Chaligne R*, Gaiti F*, Silverbush D*, Schiffman J*,…, Suvà M, Landau D. “Epigenetic encoding, heritability and plasticity of glioma transcriptional cell states”, Nature Genetics, 2021, PMID: 34594037
  7. Silverbush D and Sharan R. “A systematic approach to orient the human protein–protein interaction network”, Nature Communications, 2019, PMID: 31289271
  8. Silverbush D*#, Cristea S*#, Yanovich-Arad G, Geiger T, Beerenwinkel N and Sharan R. “Simultaneous Integration of Multi-omics Data Improves the Identification of Cancer Driver Modules”, Cell Systems, 2019, PMID: 31103572
  9. Venkatesh H, Morishita W, Geraghty A, Silverbush D,…, Monje M. “Electrical and synaptic integration of glioma into neural circuits”, Nature, 2019, PMID: 31534222
  10. Neftel C*, Laffy J*, Filbin M*, Hara T*,…, Silverbush D,…, Tirosh I, Suvà M. “An Integrative Model of Cellular States, Plasticity, and Genetics for Glioblastoma”, Cell, 2019, PMID: 31327527
  11. Silverbush D*, Grosskurth S*, Wang D, Powell F, Gottgens B, Dry J and Fisher J. “Cell-specific computational modeling of the PIM pathway in acute myeloid leukemia”, Cancer Research, 2017, PMID: 27965317
  12. Silverbush D and Sharan R. “Network orientation via shortest paths”, Bioinformatics, 2014, PMID: 24470573
  13. Silverbush D*, Elberfeld M* and Sharan R. “Optimally Orienting Physical Networks”, Journal Computational Biology, 2011,PMID: 21999286

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