Vonderheide Lab
Robert H. Vonderheide, MD, DPhil
Director Abramson Cancer Center, John H. Glick, MD Abramson Cancer Center’s Director Professor
Robert H. Vonderheide, MD, DPhil, is Director, Abramson Cancer Center, Perelman School of Medicine at the University of Pennsylvania and the John H. Glick, MD Abramson Cancer Center’s Director Professor. Dr. Vonderheide graduated from Oxford University as a Rhodes Scholar, and Harvard Medical School. He completed training in internal medicine and medical oncology at the Massachusetts General Hospital and the Dana Farber Cancer Institute. Dr. Vonderheide is a distinguished scientist and clinician who has deciphered mechanisms of cancer immune surveillance and developed novel cancer therapeutics, particularly in pancreatic cancer. He is well-recognized for driving the development of agonist CD40 antibodies, now in later stage clinical trials as potential immune therapy of cancer. Dr. Vonderheide discovered telomerase as a universal tumor antigen and has led the efforts to develop telomerase vaccination for both therapy and the prevention of cancer in healthy individuals. He has helped lead a team to show that stereotactic radiation therapy in combination with dual checkpoint blockade represents a synergistic path for immune activation in cancer. Dr. Vonderheide merges his clinical investigations with rigorous studies in mouse models or other laboratory systems. Dr. Vonderheide has been continuously funded by the NCI, and his high-impact findings have been published in Nature, Science, Cell and the New England Journal of Medicine.
Research Interests
Dr. Vonderheide's interests include deciphering mechanisms of cancer immune surveillance and developing novel cancer therapeutics.
Contact
Robert H. Vonderheide, MD, DPhil
Director, Abramson Cancer Center
John H. Glick, MD Abramson Cancer Center's Director Professor
Perelman School of Medicine
University of Pennsylvania
12 South Pavilion Expansion
3400 Civic Center Blvd
Philadelphia, PA 19104
215-662-3929
rhv@upenn.edu