Clinical Cell and Vaccine Production Facility (CVPF)

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The Clinical Cell and Vaccine Production Facility (CVPF) renders bench-to-bedside translational medicine a reality. Equipped with state-of-the-art facilities, the CVPF manufactures cell and gene biotherapeutics and has been accredited by the Foundation for the Accreditation of Cellular Therapy (FACT) since 2008. As a shared resource within the Center for Cellular Immunotherapies (CCI) and the Division of Transfusion Medicine & Therapeutic Pathology within the Department of Pathology & Laboratory Medicine, the CVPF supports numerous investigational new drug (IND) protocols. Current protocols target a variety of disease indications (primarily HIV, adult and pediatric cancers, and autoimmune disorders); many more trials are in development and, once approved, will further expand the scope of diseases targeted for cell and gene therapy. For more information on current trials, see our Clinical Trials page.

Recent News & Highlights

Ring That Bell, A Song of Hope for Cancer Patients and Survivors

May 2025

“Ring That Bell” tells the emotional story of a cancer patient facing relapse and the fierce advocacy, support, and groundbreaking science that offer new hope. Co-Written by Mags McCarthy and Bruce Levine

Merkin Prize in Biomedical Technology

October 2025

Carl June, Bruce Levine, Isabelle Rivière, and Michel Sadelain receive the 2025 Merkin Prize at the Broad Institute for chimeric antigen receptor (CAR) T-cell therapy

Recent & Upcoming Events

The Believe Ball

September 26, 2026

The Believe Ball is the Foundation’s signature fundraising event where patients and their families, leaders in the advanced therapies community, and esteemed guests and supporters gather in Philadelphia, the city where Emily Whitehead became the first pediatric patient treated with CAR T-cell therapy.

ISCT Conference Dublin

May 6-9, 2026 Dublin, Ireland

At the ISCT Annual Meeting in Dublin in May 2026, the Clinical Cell and Vaccine Production Facility (CVPF) will be represented with an exhibitor booth, and Dr. Bruce Levine will present on advances in cell therapy manufacturing and clinical translation.

Clinical Cell and Vaccine Production Facility (CVPF)