Beckman Center for Cryo-Electron Microscopy

New User

Please contact us if you have a sample for screening or data collection on the Titan Krios. Send us an email cryo-EM@lists.upenn.edu and include the sample submission form (Form)attached with the request. To check microscope availabiliy Click here

Once your grids are ready, submit them to staff members (Prerana or Sudheer) at the Singh Center.

Cryo-EM Screening

We provide both shorter Cryo-EM Screening sessions (shorter than 6 hours) as well as longer than 6–12 hour Cryo-EM sample screening sessions. The time slots will be awarded on a first-come, first-served basis. Users who wish to submit grids for screening should get in line by sending an email to cryo-em@lists.upenn.edu and expect a wait time of 1-2 weeks (this may change based on demand).

The price for 6 hours of screening is $250 (plus $18 per grid for the clip rings) and users can expect to screen 4-6 grids in a 6-hour session. 

The shorter screening sessions that are less than 6 hours of Microscope time are charged @ $50/hr

High-Res Data collection

We provide 24-72 hour sessions for High-Res data collection of pre-screened Cryo-EM grids.

Training

Anyone who is interested; especially frequent users; can receive hands-on training and learn how to drive an EPU to perform screening, assisted by Beckman Cryo-EM Center staff. Users interested in training should mention this when signing up for a screening session, as they will need to be approved for access to Singh Center which currently does not allow any visitors. 

As a reminder, the Beckman Center for Cryo-Electron Microscopy is designated as a BSL-1 facility. If your project requires BSL-2, please contact the CEMAC committee for further discussion.

Rates

CURRENT RATES FOR HIGH-RESOLUTION CRYO-ELECTRON MICROSCOPY

• Internal Independent Use (UPenn and CHOP only): $1,000.00/day + $18.00/C-Clip
• Academic Independent Use (Temple, Drexel, Jefferson, etc.): $1,630.00/day + $28.50/C-Clip
• Corporate Independent Use (External): $2,000.00/day + $28.50/C-Clip

iLab Setup

The next step after you fill the consultation form is to set up your iLab account to access services. Learn more about iLab setup.