Beckman Center for Cryo-Electron Microscopy

New User

All New Users are required to email for a consultation ( Once you send the email with your request, we will get back to you about the project's feasibility, pricing, and goals.

Cryo-EM Screening

We provide both shorter Cryo-EM Screening sessions (shorter than 6 hours) as well as longer than 6–12 hour Cryo-EM sample screening sessions. The time slots will be awarded on a first-come, first-served basis. Users who wish to submit grids for screening should get in line by sending an email to and expect a wait time of 1-2 weeks (this may change based on demand).

The price for 6 hours of screening is $250 (plus $18 per grid for the clip rings) and users can expect to screen 4-6 grids in a 6-hour session. 

The shorter screening sessions that are less than 6 hours of Microscope time are charged @ $50/hr

High-Res Data collection

We provide 24-72 hour sessions for High-Res data collection of pre-screened Cryo-EM grids.


Anyone who is interested; especially frequent users; can receive hands-on training and learn how to drive an EPU to perform screening, assisted by Beckman Cryo-EM Center staff. Users interested in training should mention this when signing up for a screening session, as they will need to be approved for access to Singh Center which currently does not allow any visitors. 

As a reminder, the Beckman Center for Cryo-Electron Microscopy is designated as a BSL-1 facility. If your project requires BSL-2, please contact the CEMAC committee for further discussion.



  • Internal Independent Use (UPenn and CHOP only): $1,000.00/day + $18.00/C-Clip
  • Academic Independent Use (Temple, Drexel, Jefferson, etc.): $1,630.00/day + $28.50/C-Clip
  • Corporate Independent Use (External): $2,000.00/day + $28.50/C-Clip

iLab Setup

The next step after you fill the consultation form is to set up your iLab account to access services. Learn more about iLab setup.




Crossbeam 550 + Meteor

1.Zeiss LSM900 Confocal - 2.Airyscan - 3.Linkam cryostage CMS196 - 4.Zen Connect Blue 

ZEISS LSM900 confocal Airyscan
1.Zeiss LSM900 Confocal - 2.Airyscan - 3.Linkam cryostage CMS196 - 4.Zen Connect Blue 


Leica EM GP2

VITROBOT - Thermoscientific

Krios G3i