About the PI
Dr. Fan earned his MD from Shanghai University of Traditional Chinese Medicine in 1999 and his PhD in Pathology from Case Western Reserve University in 2009. After completing postdoctoral training in vascular biology at the Cleveland Clinic, he joined the faculty at the University of Pennsylvania, where he has advanced to the rank of tenured Professor. His research centers on uncovering the regulatory mechanisms governing tissue vascularity and immunity in disease progression, with the overarching goal of developing innovative therapies to reprogram the tissue microenvironment for treating cancer and cardiovascular diseases.
Awards to Dr. Fan
2025 Elected member, American Society for Clinical Investigation (ASCI)
2024 Yosemite Award, American Cancer Society (ACS)
2019 Research Excellence Award, American Heart Association (AHA)
2019 Sharpe Award (GBM research award), National Brain Tumor Society (NBTS)
2018 Springer Award (for Junior Investigator), North American Vascular Biology Organization (NAVBO)
2018 Innovative Project Award, American Heart Association (AHA)
2018 Young Investigator Award, Cancer Stem Cell Conference, Cleveland, OH
2017 Early Career Investigator Award, Radiation Research Society (RRS)
2017/2018 Brain Cancer Investigator Award, B*Cured Foundation
2017 Sharpe Award (Brain tumor research award), National Brain Tumor Society (NBTS)
2016 Judah Folkman Award (Career award for angiogenesis research), AACR
2015 Young Investigator Award of Excellence (RadOnc), Hospital of the University of Pennsylvania
2015 Neuro-Oncology Innovation Award, University of Pennsylvania Abramson Cancer Center
2015 McCabe Award, University of Pennsylvania Perelman School of Medicine
2013 NIH Pathway to Independence Award, NIH/NHLBI
2013 Scientist Development Grant Award, American Heart Association
2013 Elsa Albrecht Award, Cleveland Clinic, Cleveland, OH
2013 Robert Tarazi Award, Cleveland Clinic, Cleveland, OH
2010 Elsa Albrecht Award, Cleveland Clinic, Cleveland, OH
2010 NHLBI Scholarship, “Angiogenesis in Health and Disease” Symposia, Keystone, CO
2009 Graduate Student Fellowship Award, Cleveland Clinic, Cleveland, OH
2008 Travel Award, “Frontier in Cell Migration” Conference, NIH Bethesda, MD
Awards to Trainees
2025 American Heart Association (AHA) Predoctoral Fellowship award 25PRE1360091, to Xinye Ashley Zhao (PhD student)
2024 Travel Award, International Tumor Microenvironment Stress Conference, to Prithvi Sinha (PhD student)
2024 Dr. Stephen Tuttle Research Award, University of Pennsylvania, to Yasmin Jackson (SUPERS student)
2024 Graduate Student Scholarship, Gerondelis Foundation, to Elisavet Krimitza (PhD student)
2023 Marshall Scholarship, British government, to Gina Ngo (SUPERS student)
2023 NIH/NCI F99/K00 Award, Christian Figueroa-Espada (Co-mentor, Yi Fan; Primary mentor, Michael Mitchell)
2022 NAVBO Travel Award, International Vascular Biology Meeting, October 13-17, 2022, Oakland, CA, to Duo Zhang (PhD student)
2022 James Blair Undergraduate Research Fellow (summer research fellowship), to Gloria Lee (research student)
2022 PURM award (summer research fellowship), to Katherine Han (research student)
2021 Outstanding Poster Award, Vascular Biology 2021, North American Vascular Biology Organization (NAVBO) annual conference, to Menggui Huang (postdoc fellow)
2021 American Heart Association (AHA) Predoctoral fellowship award 830890, to Duo Zhang
2020 NIH T32/GM008076 fellowship award, to Zachary Lamplugh (PhD student)
2015 American Association for Cancer Research (AACR) Scholar-in-Training Award, to Menggui Huang (postdoc fellow)
Contact Us

Fan Laboratory
Department of Radiation Oncology
University of Pennsylvania
3400 Civic Center Blvd
Smilow Center for Translational Research
Rm 8-132 (Office); Rm 8-167 (Lab)
Philadelphia, PA 19104
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