Publications

Zhang T, Rawal Y, Jiang H, Kwon Y, Sung P, Greenberg RA. Break-Induced Replication Orchestrates resection dependent template switching. Nature 2023 Jul;619(7968):201-208. doi: 10.1038/s41586-023-06177-3. Epub 2023 Jun 14.

Jiang Q, Foglizzo M, Morozov YI, Yang X, Datta A, Tian L, Thada V, Li W, Zeqiraj E, Greenberg RA. Autologous K63 deubiquitylation within the BRCA1-A complex licenses DNA damage recognition. J Cell Biol. 2022 Sep 5;221(9):e202111050.

Verma P, Greenberg RA. Communication between chromatin and homologous recombination. Curr Opin Genet Dev. 2021 Jun 4;71:1-9.

Vessoni AT, Zhang T, Quinet A, Jeong H-C, Munroe M, Wood M, Tedone E, Vindigni A, Shay JW, Greenberg RA, Batista L FZ. Telomere erosion in human pluripotent stem cells leads to ATR-mediated mitotic catastrophe. J Cell Biol. 2021 Jun 7;220(6):e202011014.

Lippert TP, Greenberg RA. The abscopal effect: a sense of DNA damage is in the air. J Clin Invest. 2021 May 3;131(9):e148274.

Jiang H, Greenberg RA. Morning for Irofluven, What Could be fiNER? Clin Cancer Res. 2021 Apr 1;27(7):1833-1835.

Verma P, Zhou Y, Cao Z, Deraska PV, Deb M, Arai E, Li W, Shao Y, Puentes L, Li Y, Patanka S, Mach RH, Faryabi RB, Shi J*, Greenberg RA*. ALC1 links chromatin accessibility to PARP inhibitor response in homologous recombination-deficient cells. Nat Cell Biol. 2021 Feb;23(2):160-171. Notes: *co-corresponding authors doi: 10.1038/s41556-020-00624-3.

Chen J, Harding SM, Natesan R, Tian L, Benci JL, Li W, Minn AJ, Asangani IA, Greenberg RA. Cell Cycle Checkpoints Cooperate to Suppress DNA- and RNA-Associated Molecular Pattern Recognition and Anti-Tumor Immune Responses. Cell Rep. 2020 Sep 1;32(9):108080.

Zhang H, Zhao R, Tones J, Liu M,  Dilley RL, Chenoweth DM, Greenberg RA, Lampson MA. Nuclear body phase separation drives telomere clustering in ALT cancer cells. Mol Biol Cell 2020 Aug 15;31(18):2048-2056. doi: 10.1091/mbc.E19-10-0589.

Walden M*, Tian L*, Ross R, Sykora UM, Byrne DP, Hesketh EL, Masandi SK, Cassel J, Geirge R, Ault JR, Oualid FE, Pawlowski K, Salvino JM, Eyers PA, Ranson NA, Del Galdo F, Greenberg RA#, Zeqiraj E#. Metabolic control of BRISC-SHMT2 complex assembly regulates immune signaling. Nature Jun;570(7760):194-199 2019. Notes: *co-first authors and # co-corresponding authors.

Verma P1, Dilley RL#1, Zhang T#1, Gyparaki MT1, Li Y1, Greenberg RA. RAD52 and SLX4 act nonepistatically to ensure telomere stability during alternative telomere lengthening. Genes Dev. 2019 Feb 1;33(3-4):221-235.

Greenberg RA. Assembling a protective shield. Nat Cell Biol. 2018 Aug;20(8):862-863.

Li ML, Jiang Q, Bhanu NV, Wu J, Li W, Garcia BA, Greenberg RA. Phosphorylation of TIP60 Suppresses 53BP1 Localization at DNA Damage Sites. Mol Cell Biol. 2018 Dec 11;39(1). pii: e00209-18.

Harding SM, Benci JL, Irianto J, Discher DE, Minn AJ, Greenberg RA. Mitotic progression following DNA damage enables pattern recognition within micronuclei. Nature 548: 466-470, 2017.

Dilley RL, Verma P, Cho NW, Winters HD, Wondisford AR, Greenberg RA. Break-induced telomere synthesis underlies alternative telomere maintenance. Nature 2016 Nov 3;539(7627):54-58. Notes: Comment in Nature: DNA Repair: Telomere-lengthening mechanism revealed. Roake CM, Artandi SE. Nature 2016 Oct 19. doi: 10.1038/nature19483.

Cho NW, Dilley RL, Lampson MA, Greenberg RA: Interchromosomal Homology Searches Drive Directional ALT Telomere Movement and Synapsis. Cell 159(1): 108-21, 2014.

Sawyer SL, Tian L, Kähkönen M, Schwartzentruber J, Kircher M; University of Washington Centre for Mendelian Genomics; FORGE Canada Consortium, Majewski J, Dyment DA, Innes AM, Boycott KM, Moreau LA, Moilanen JS, Greenberg RA. Biallelic mutations in BRCA1 cause a new Fanconi anemia subtype. Cancer Discov. 2015 Feb;5(2):135-42.

Verma P, Greenberg RA. Noncanonical views of homology-directed DNA repair. Genes Dev. 2016 May 15;30(10):1138-54.

Sobhian B, Shao G, Lilli DR, Culhane AC, Moreau LA, Xia B, Livingston DM, Greenberg RA. RAP80 targets BRCA1 to specific ubiquitin structures at DNA damage sites. Science 2007 May 25;316(5828):1198-202.

Shao G, Patterson-Fortin J, Messick TE, Feng D, Shanbhag N, Wang Y, Greenberg RA. MERIT40 controls BRCA1-Rap80 complex integrity and recruitment to DNA double-strand breaks. Genes Dev. 2009 Mar 15;23(6):740-54.

Shanbhag NM, Rafalska-Metcalf IU, Balane-Bolivar C, Janicki SM, Greenberg RA. ATM-dependent chromatin changes silence transcription in cis to DNA double-strand breaks. Cell 2010 Jun 11;141(6):970-81.

Greenberg RA. BRCA1, Everything but the ring? Science 2011 Oct 28;334(6055):459-60.

Tang J, Cho NW, Cui G, Manion EM, Shanbhag NM, Botuyan MV, Mer G, Greenberg RA. Acetylation limits 53BP1 association with damaged chromatin to promote homologous recombination. Nat Struct Mol Biol. 2013 Mar;20(3):317-25.

Zheng H#, Gupta V#, Patterson-Fortin J#, Bhattacharya S#, Katlinski K, Wu J, Varghese B, Carbone CJ, Aressy B, Fuchs SY*, Greenberg RA*. A BRISC-SHMT complex deubiquitinates IFNAR1 and regulates interferon responses. Cell Rep. 2013 Oct 17;5(1):180-93. Notes: # co-first author * co-corresponding author.

Cho NW, Greenberg RA. DNA repair: Familiar ends with alternative endings. Nature 2015 Feb 12;518(7538):174-6.

Zeqiraj E, Tian L, Piggott CA, Pillon MC, Duffy NM, Ceccarelli DF, Keszei AF, Lorenzen K, Kurinov I, Orlicky S, Gish GD, Heck AJ, Guarné A, Greenberg RA*, Sicheri F*. Higher-Order Assembly of BRCC36-KIAA0157 Is Required for DUB Activity and Biological Function. Mol Cell 2015 Sep 17;59(6):970-83. Notes: *co-corresponding authorship.

Jiang Q, Paramasivam M, Aressy B, Wu J, Bellani M, Tong W, Seidman MM, Greenberg RA. MERIT40 cooperates with BRCA2 to resolve DNA interstrand cross-links. Genes Dev. 2015 Sep 15;29(18):1955-68.