CryoEM structure of an MHC-I/TAPBPR peptide-bound intermediate reveals the mechanism of antigen proofreading.

Sun Y, Pumroy RA, Mallik L, Chaudhuri A, Wang C, Hwang D, Danon JN, Dasteh Goli K, Moiseenkova-Bell VY, Sgourakis NG. Proc Natl Acad Sci U S A. 2025 Jan 14;122(2):e2416992122. doi: 10.1073/pnas.2416992122. Epub 2025 Jan 9. PMID: 39786927