Recognition | I3H MODX Implementation | Perelman School of Medicine at the University of Pennsylvania

AACR Panelists Call on Scientists to Stand Up Against Cuts That Threaten Progress, Patients, and Future Discoveries

During a discussion, “Cancer Research at a Crossroads,” at the 2025 AACR Annual Meeting, panelists said scientists must teach the public why cancer research matters—and how recent grant cancellations and policy decisions could bring unprecedented progress to a grinding halt....

The Philly-Area Doctors and Technology Revolutionizing the Future of Aging

From sleep issues to Alzheimer’s to antibiotic resistance, three Penn researchers are taking aim at some of the more daunting aspects of aging. Joseph Baur, PhD, a professor of Physiology; César de la Fuente, PhD, a Presidential Associate...

Targeting KRAS in Lung Cancer: Spotlight on G12D

“Widely anticipated and incredibly promising” preliminary findings from a phase I study presented at the 2025 AACR Annual Meeting showed that the drug zoldonrasib, which targets active KRASG12D, is safe and has encouraging efficacy in patients with non–small cell lung...

How Common Bacteria Can Accelerate Diabetic Wound Closure

A certain bug, Alcaligenes faecalis (A. faecalis), can facilitate healing of hard-to-treat wounds among people with diabetes, according to new research led by Elizabeth Grice, MD, of Dermatology. Grice told MSN that “we did not expect to...

Could New Tech Prevent Aerial Virus Transmission?

Right now, bird flu doesn’t spread from person to person through the air, but Scott Hensley, PhD, of Microbiology, explained to CBS Evening News that just a few small mutations could change that, with the potential to greatly impact...

‘Don’t Eat Me’ Marker Boosts Efficiency of mRNA Therapy

Messenger RNA (mRNA) therapies could be more effective in reaching their targets when their rides, lipid nanoparticles, are marked with a protein called CD47, that transmits a “Don’t eat me” signal to immune cells, according to a study by researchers...

Key NIH Vaccine Center Slammed by Contract Cuts

The National Institute of Health’s (NIH’s) Vaccine Research Center (VRC), once a roughly 400-person workforce that helped develop and clinically test vaccines and antibody treatments for Ebola and other infectious diseases, has seen significant staff reductions. Launched 25 years ago,...

Antiviral AI

Researchers at the Perelman School of Medicine combined AI algorithms with traditional laboratory methods to uncover promising drug leads against human enterovirus, the pathogen behind most cases of hand, foot, and mouth disease. “The approach is especially powerful when time,...

Oncology Experts Highlight Top Takeaways From the 2025 AACR Annual Meeting

Experts from across oncology specialties shared some of the most talked-about abstracts and discussions from the 2025 AACR Annual Meeting. Ronny Drapkin, MD, PhD the Franklin Payne Professor of Pathology in Obstetrics & Gynecology, noted research to better understand features...

TIME100 Health: David Fajgenbaum

TIME’s list of the “most influential voices leading the way” in health for 2025 includes David Fajgenbaum, MD, MBA, an associate professor of Translational Medicine & Human Genetics. He survived Castleman disease by discovering an existing drug could save...

Scientists Hail This Medical Breakthrough. A Political Storm Could Cripple It.

Scientists have proven the potential of mRNA technology to greatly impact health—from COVID-19 vaccines to cancer therapies to chronic disease. However, state and federal lawmakers are canceling mRNA research through fund withholding and proposed legislation. “The consequences are enormous. It...

Enhanced CAR T cell therapy offers new strategy for lymphoma

A new study from Penn Medicine marks a significant development in the ongoing evolution of CAR T cell therapy, as a novel cytokine-enhanced CAR T that has been tested in patients with blood cancer shows robust response rates. Led by...

Science Caught in the Crossfire of Federal Funding Freezes

Federal funding freezes to universities are being portrayed by the new presidential administration as a temporary measure to force policy changes and address antisemitism on campuses, but scientists see long-term negative impacts on a tradition of partnerships between the government...

David Fajgenbaum’s ‘Chasing My Cure’ Being Developed as Medical Thriller

A pair of producers plan to create a feature film out of “Chasing My Cure,” the story of David Fajgenbaum, MD, MBA, an assistant professor of Translational Medicine and Human Genetics, searching for a treatment for his rare Castleman...

Understanding the Cellular Drivers of MS Progression and Treatment Response

At the American Academy of Neurology Annual Meeting, Amit Bar-Or, MD, director of the Center for Neuroinflammation and Neurotherapeutics, discussed recent advances in understanding the cellular immunology of Multiple Sclerosis (MS), emphasizing the role of immune cells. He highlighted...

Beyond the Breakthrough: Industry Leaders Address Key Hurdles Facing Cell and Gene Therapies

During a keynote presentation at the 2025 GenScript Biotech Global Forum, CAR T cell therapy pioneer Carl June, MD, the Richard W. Vague Professor in Immunotherapy, shared his perspective on 2024 being a breakthrough year for cell and gene...

Could a New Technology Prevent the Transmission of Viruses Through the Air?

Right now, bird flu doesn’t spread from person-to-person through the air, but Scott Hensley, PhD, a professor of Microbiology, explained that just a few small mutations could change that, with the potential to greatly impact humans. A new technology...

Washington State Man Credits AI Treatment for Saving His Life

Joseph Coates was suffering from an enlarged heart and failing kidneys due to POEMS syndrome. But thanks to David Fajgenbaum, MD, MBA, an assistant professor of Translational Medicine & Human Genetics, artificial intelligence was used to comb through treatments...

Education and Professional Development Sessions at 2025 AACR Annual Meeting

Preview coverage of the 2025 AACR Annual Meeting highlights an Education Session chaired by Marco Ruella, MD, an assistant professor of Hematology-Oncology, and a Professional Development Session co-chaired by Carmen Guerra, MD, the Ruth C. and Raymond G....

Annual Meeting to Recognize 33 New Fellows of the AACR Academy

Distinguished cancer researchers Garrett M. Brodeur, MD, Susan Domchek, MD, Stephan Grupp, MD, PhD, and Robert Vonderheide, MD, DPhil, from the Perelman School of Medicine and the Abramson Cancer Center have been elected to the 2025...