• Purified human CD8 T-cells

    Erin Zwack/Brodsky Lab & Penn Vet Imaging Core - Murine macrophages infected with Yersinia pseudo tuberculosis. Blue indicates the cell, red is a mitochondrial stain, green is a stain for Yersinia secreted effector proteins.

  • 3D image of the inflamed meningeal membrane of a CX3CR1-GFP reporter mouse

    Claudio Giraudo - Polarization of lytic granules to the immunological synapse during the cytolytic process of human CD8 lymphocytes against cancer cells.

  • Time series of cells expressing GFP-tagged ebola viral protein VP40

    Gretchen Harms, Hunter lab - Stylized images of CD8+ T cells looking at differential localization of the transcription factor T-bet in mouse cells after infection with the parasite Toxoplasma gondii, using the Amnis ImageStream. In the cell in the first and third box, T-bet (red) does not co-localize with DAPI (blue), indicating that it is cytoplas


Our Mission

*Advance our knowledge of the basic immunology of inflammation, autoimmunity, cancer, transplantation and infection and to translate this new knowledge to novel strategies for diagnosis, prevention and therapeutic intervention. 

*Foster collaborations and further strengthen interactions among the Penn community of immunologists.

Spotlights on IFI


Dr. Christopher Hunter, PhD, of the University of Pennsylvania School of Veterinary Medicine, has been named the Mindy Halikman Heyer President’s Distinguished Professor.

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2015 Penn Medicine Awards of Excellence

Congratulations to our IFI winners:

Andy J. Minn, MD, PhD  Michael S. Brown New Investigator Research Award

Edward M. Behrens, MD —The Lady Barbara Colyton Prize for Autoimmune Research Award

Alain H. Rook, MD —Louis Duhring Outstanding Clinical Specialist Award

Penn Researchers Receive $2.9 Million in Awards from the Burroughs Wellcome Fund to Launch Biomedical Research Careers

Congratulations to Igor Brodsky, PhD and Rahul Kohli, MD, PhD for receiving the Investigators in the Pathogenesis of Infectious Disease Award from the Burroughs Welcome Fund.

CRI Irvington Postdoctoral Fellows: A Passion for Science

Postdoctoral fellows are the engine of biomedical research. Hear what it's like to be a Cancer Research Institute (CRI) postdoctoral fellow from those who have devoted their lives to the pursuit of basic research in cancer immunology. Featuring Beth Stadmueller, PhD, Roy Maute, PhD, Matthew Gubin, PhD, Paola Betancur, PhD, Kristen Pauken, PhD, E. John Wherry, PhD, and Ellen Puré, PhD.

Established in 1971, the CRI Irvington Postdoctoral Fellowship Program is the oldest of CRI's grant initiatives. To date, CRI has supported more than 1,300 fellows and invested more than $115 million in their training at laboratories all over the world. CRI is the only nonprofit organization devoted exclusively to funding research in the areas of cancer immunology and immunotherapy, with the goal of developing more effective immune-based treatments for all cancers.

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Penn Study Identifies Viral Product That Promotes Immune Defense Against RSV

Faculty member Carolina López, PhD and members of her lab recently published their work on respiratory syncytial virus (RSV) in PLOS Pathogens. In this paper, Dr. López and her lab describe a subset of viral products that elicit a strong immune response against RSV in people who become infected.
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Congratulations to the 2015 IFI Pilot Awardees:

Jorge Henao Mejia, MD, PhD, Assistant Professor of Pathology and Laboratory Medicine
LincRNAs in Inflammatory Bowel Disease

Matthew Levine, MD, PhD, Assistant Professor of Surgery
Mechanistic High Throughput Screening to Identify Means of HDAC2 Deletion-Associated Ischemia Tolerance

Immunology in the News

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