Perelman School of Medicine at the University of Pennsylvania

Penn Institute for Immunology


E. John Wherry, Ph.D.

E. John Wherry, Ph.D.
Chair, Department of Systems Pharmacology and Translational Therapeutics; Richard and Barbara Schiffrin President’s Distinguished Professor and Director, IFI

One major goal of the research in Dr. Wherry's laboratory is to understand the mechanisms of T cell exhaustion during chronic infections and cancer. A second major interest of the lab is the study of T cell memory including the biology of human T follicular helper cells (TFH). Finally, other ongoing interests in the lab include computational approaches for analysis of high dimensional cytometric, transcriptional, and epigenetic datasets, the origin of CD8 T cell memory, and other models of respiratory and intestinal viral infection.