Perelman School of Medicine at the University of Pennsylvania

Penn Institute for Immunology


While inflammation is an essential and important part of the physiological and immunological response to infection and tissue injury, prolonged or inappropriate inflammation can result in pathological situations including allergy and asthma, sepsis, respiratory distress, cardiovascular disease, autoimmunity and some forms of cancer. IFI researchers are investigating how the balance between the healthy and important aspects of inflammation and pathological consequences of dysregulated inflammation is achieved or becomes dysregulated in multiple infectious, inflammatory and metabolic disease states.