Publication list with Penn IFI CyTOF Core data

Investigators, please report any missing publications. Also please don’t forget to properly acknowledge Research Cores and the CMC VA Medical Center in your publications. . See the UPENN guideline about the use of Core facilities (https://www.med.upenn.edu/cores/acknowledging-core-facilities-in-research-publications.html).

Decade-long leukaemia remissions with persistence of CD4⁺ CAR T cells. Melenhorst JJ, Chen GM, Wang M, Porter DL, Chen C, Collins MA, Gao P, Bandyopadhyay S, Sun H, Zhao Z, Lundh S, Pruteanu-Malinici I, Nobles CL, Maji S, Frey NV, Gill SI, Tian L, Kulikovskaya I, Gupta M, Ambrose DE, Davis MM, Fraietta JA, Brogdon JL, Young RM, Chew A, Levine BL, Siegel DL, Alanio C, Wherry EJ, Bushman FD, Lacey SF, Tan K, June CH.Nature. 2022 Feb;602(7897):503-509.
T-cell exhaustion and residency dynamics inform clinical outcomes in hepatocellular carcinoma. Barsch M, Salié H, Schlaak AE, Zhang Z, Hess M, Mayer LS, Tauber C, Otto-Mora P, Ohtani T, Nilsson T, Wischer L, Winkler F, Manne S, Rech A, Schmitt-Graeff A, Bronsert P, Hofmann M, Neumann-Haefelin C, Boettler T, Fichtner-Feigl S, van Boemmel F, Berg T, Rimassa L, Di Tommaso L, Saeed A, D'Alessio A, Pinato DJ, Bettinger D, Binder H, John Wherry E, Schultheiss M, Thimme R, Bengsch B. .J Hepatol. 2022 Apr 1:S0168-8278(22)00180-5.
PTEN Loss and BRCA1 Promoter Hypermethylation Negatively Predict for Immunogenicity in BRCA-Deficient Ovarian Cancer. Kraya AA, Maxwell KN, Eiva MA, Wubbenhorst B, Pluta J, Feldman M, Nayak A, Powell DJ Jr, Domchek SM, Vonderheide RH, Nathanson KL. JCO Precis Oncol. 2022 Feb;6:e2100159.
Pembrolizumab for B-cell lymphomas relapsing after or refractory to CD19-directed CAR T-cell therapy.Chong EA, Alanio C, Svoboda J, Nasta SD, Landsburg DJ, Lacey SF, Ruella M, Bhattacharyya S, Wherry EJ, Schuster SJ. Blood. 2022 Feb 17;139(7):1026-1038.
Systematic analysis of CD39, CD103, CD137, and PD-1 as biomarkers for naturally occurring tumor antigen-specific TILs. Eiva MA, Omran DK, Chacon JA, Powell DJ Jr. Eur J Immunol. 2022 Jan;52(1):96-108.
Neoadjuvant Selicrelumab, an Agonist CD40 Antibody, Induces Changes in the Tumor Microenvironment in Patients with Resectable Pancreatic Cancer. Byrne KT, Betts CB, Mick R, Sivagnanam S, Bajor DL, Laheru DA, Chiorean EG, O'Hara MH, Liudahl SM, Newcomb C, Alanio C, Ferreira AP, Park BS, Ohtani T, Huffman AP, Väyrynen SA, Dias Costa A, Kaiser JC, Lacroix AM, Redlinger C, Stern M, Nowak JA, Wherry EJ, Cheever MA, Wolpin BM, Furth EE, Jaffee EM, Coussens LM, Vonderheide RH. Clin Cancer Res. 2021 Aug 15;27(16):4574-4586.
Analysis of classical neutrophils and polymorphonuclear myeloid-derived suppressor cells in cancer patients and tumor-bearing mice. Veglia F, Hashimoto A, Dweep H, Sanseviero E, De Leo A, Tcyganov E, Kossenkov A, Mulligan C, Nam B, Masters G, Patel J, Bhargava V, Wilkinson P, Smirnov D, Sepulveda MA, Singhal S, Eruslanov EB, Cristescu R, Loboda A, Nefedova Y, Gabrilovich DI. J Exp Med. 2021 Apr 5;218(4):e20201803.
Type 1 conventional dendritic cells are systemically dysregulated early in pancreatic carcinogenesis. Lin JH, Huffman AP, Wattenberg MM, Walter DM, Carpenter EL, Feldser DM, Beatty GL, Furth EE, Vonderheide RH. J Exp Med. 2020 Aug 3;217(8):e20190673.
Exploration of T-Cell Diversity Using Mass Cytometry. O'Boyle KC, Ohtani T, Manne S, Bengsch B, Henrickson SE, Wherry EJ, Alanio C. Methods Mol Biol. 2020;2111:1-20.
Mapping the Lineage Relationship between CXCR5₊ and CXCR5_- CD4₊ T Cells in HIV-Infected Human Lymph Nodes. Del Alcazar D, Wang Y, He C, Wendel BS, Del Río-Estrada PM, Lin J, Ablanedo-Terrazas Y, Malone MJ, Hernandez SM, Frank I, Naji A, Reyes-Terán G, Jiang N, Su LF. Cell Rep. 2019 Sep 17;28(12):3047-3060.
Common variable immunodeficiency-associated endotoxemia promotes early commitment to the T follicular lineage. Le Coz C, Bengsch B, Khanna C, Trofa M, Ohtani T, Nolan BE, Henrickson SE, Lambert MP, Kim TO, Despotovic JM, Feldman S, Fadugba OO, Takach P, Ruffner M, Jyonouchi S, Heimall J, Sullivan KE, Wherry EJ, Romberg N. J Allergy Clin Immunol. 2019 Aug 21. pii: S0091-6749(19)31092-9.
Multiplexed In Situ Imaging Mass Cytometry Analysis of the Human Endocrine Pancreas and Immune System in Type 1 Diabetes. Wang YJ, Traum D, Schug J, Gao L, Liu C; HPAP Consortium, Atkinson MA, Powers AC, Feldman MD, Naji A, Chang KM, Kaestner KH. Cell Metab. 2019 Mar 5;29(3):769-783.
Epigenomic-Guided Mass Cytometry Profiling Reveals Disease-Specific Features of Exhausted CD8 T Cells. Bengsch B, Ohtani T, Khan O, Setty M, Manne S, O'Brien S, Gherardini PF, Herati RS, Huang AC, Chang KM, Newell EW, Bovenschen N, Pe'er D, Albelda SM, Wherry EJ. Immunity. 2018 May 15;48(5):1029-1045.
The receptor repertoire and functional profile of follicular T cells in HIV-infected lymph nodes. Wendel BS, Del Alcazar D, He C, Del Río-Estrada PM, Aiamkitsumrit B, Ablanedo-Terrazas Y, Hernandez SM, Ma KY, Betts MR, Pulido L, Huang J, Gimotty PA, Reyes-Terán G, Jiang N, Su LF. Sci Immunol. 2018 Apr 6;3(22). pii: eaan8884.
Deep immune profiling by mass cytometry links human T and NK cell differentiation and cytotoxic molecule expression patterns. Bengsch B, Ohtani T, Herati RS, Bovenschen N, Chang KM, Wherry EJ. J Immunol Methods. 2018 Feb;453:3-10.