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    Laura McLane and Mike Betts -Purified human CD8 T-cells were stained with a-T-bet (green), a-Lamin A (pink), and DAPI (blue) and imaged on a multilaser-based spinning disk confocal microscope (Zeiss). T-bet can be localized to both the nuclear and cytoplasmic compartments of specific subsets of human CD8 T-cells.

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    3D image of the inflamed meningeal membrane of a CX3CR1-GFP reporter mouse infected with Toxoplasma gondii. The dura mater that surrounds the brain is blue, blood vessels are labeled red and microglia and macrophages are green. Contributors for image are ChristophKonradt and Chris Hunter.

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    Time series of cells expressing GFP-tagged ebola viral protein VP40, pseudocolored as a fluorescence intensity heatmap. The contributors for image are: Gordon Ruthel, Xiaohong Liu, Ron Harty, and Bruce Freedman.


Mouse Strain Collection DataClick here for a list of current mouse strains available on campus

Immunotherapy in the Department of Pathology and Laboratory Medicine


I3-IBD Immunology Initiative

I3 is a translational clinical and tissue database study that is actively enrolling all Crohn’s disease and Ulcerative Colitis patients seen within the University of Pennsylvania Health System. The aim is to understand abnormalities in the immune system and other factors that impact IBD.
Investigators: Meenakshi Bewtra, M.D.
Coordinator Contact: Tram Hoang <Tram.Hoang@uphs.upenn.edu>

School of Medicine

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Clinical Health Service Research Core:

Center for Molecular Studies in Digestive and Liver Diseases:

SOM Screening Core

School of Arts and Sciences

School of Dental Medicine

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