Selected Publications

 

1. Bitter taste receptor agonists regulate epithelial two-pore potassium channels via cAMP signaling.

Kohanski MA, Brown L, Orr M, Tan LH, Adappa ND, Palmer JN, Rubenstein RC, Cohen NA.Respir Res. 2021 Jan 28;22(1):31. doi: 10.1186/s12931-021-01631-0.PMID: 33509163

 

2. Review of indoor aerosol generation, transport, and control in the context of COVID-19.

Kohanski MA, Lo LJ, Waring MS.Int Forum Allergy Rhinol. 2020 Oct;10(10):1173-1179. doi: 10.1002/alr.22661. Epub 2020 Jul 24.PMID: 32652898 

 

3. Solitary chemosensory cells are innervated by trigeminal nerve endings and autoregulated by cholinergic receptors.

Deng J, Tan LH, Kohanski MA, Kennedy DW, Bosso JV, Adappa ND, Palmer JN, Shi J, Cohen NA.Int Forum Allergy Rhinol. 2020 Oct 11. doi: 10.1002/alr.22695. Online ahead of print.PMID: 33040489

 

4. Solitary chemosensory cells are a primary epithelial source of IL-25 in patients with chronic rhinosinusitis with nasal polyps.

Kohanski MA, Workman AD, Patel NN, Hung LY, Shtraks JP, Chen B, Blasetti M, Doghramji L, Kennedy DW, Adappa ND, Palmer JN, Herbert DR, Cohen NA.J Allergy Clin Immunol. 2018 Aug;142(2):460-469.e7. doi: 10.1016/j.jaci.2018.03.019. Epub 2018 May 17.PMID: 29778504

 

5. Solitary chemosensory cells producing interleukin-25 and group-2 innate lymphoid cells are enriched in chronic rhinosinusitis with nasal polyps.

Patel NN, Kohanski MA, Maina IW, Triantafillou V, Workman AD, Tong CCL, Kuan EC, Bosso JV, Adappa ND, Palmer JN, Herbert DR, Cohen NA.Int Forum Allergy Rhinol. 2018 May 9:10.1002/alr.22142. doi: 10.1002/alr.22142. Online ahead of print.PMID: 29742315

 

6. Cellular context of IL-33 expression dictates impact on anti-helminth immunity.

Hung LY, Tanaka Y, Herbine K, Pastore C, Singh B, Ferguson A, Vora N, Douglas B, Zullo K, Behrens EM, Li Hui Tan T, Kohanski MA, Bryce P, Lin C, Kambayashi T, Reed DR, Brown BL, Cohen NA, Herbert DR.Sci Immunol. 2020 Nov 13;5(53):eabc6259. doi: 10.1126/sciimmunol.abc6259.PMID: 33188058

 

7. SARS-CoV-2 induces double-stranded RNA-mediated innate immune responses in respiratory epithelial derived cells and cardiomyocytes.

Li Y, Renner DM, Comar CE, Whelan JN, Reyes HM, Cardenas-Diaz FL, Truitt R, Tan LH, Dong B, Alysandratos KD, Huang J, Palmer JN, Adappa ND, Kohanski MA, Kotton DN, Silverman RH, Yang W, Morrisey E, Cohen NA, Weiss SR.bioRxiv. 2020 Sep 25:2020.09.24.312553. doi: 10.1101/2020.09.24.312553. Preprint.PMID: 32995797 

 

8. Clinically relevant mutations in core metabolic genes confer antibiotic resistance.

Lopatkin AJ, Bening SC, Manson AL, Stokes JM, Kohanski MA, Badran AH, Earl AM, Cheney NJ, Yang JH, Collins JJ.Science. 2021 Feb 19;371(6531):eaba0862. doi: 10.1126/science.aba0862.PMID: 33602825

 

9. How antibiotics kill bacteria: from targets to networks.

Kohanski MA, Dwyer DJ, Collins JJ.Nat Rev Microbiol. 2010 Jun;8(6):423-35. doi: 10.1038/nrmicro2333. Epub 2010 May 4.PMID: 20440275 Free PMC article. Review.

 

10. Sublethal antibiotic treatment leads to multidrug resistance via radical-induced mutagenesis.

Kohanski MA, DePristo MA, Collins JJ.Mol Cell. 2010 Feb 12;37(3):311-20. doi: 10.1016/j.molcel.2010.01.003.PMID: 20159551 

 

11. Mistranslation of membrane proteins and two-component system activation trigger antibiotic-mediated cell death.

Kohanski MA, Dwyer DJ, Wierzbowski J, Cottarel G, Collins JJ.Cell. 2008 Nov 14;135(4):679-90. doi: 10.1016/j.cell.2008.09.038.PMID: 19013277 

 

12. A common mechanism of cellular death induced by bactericidal antibiotics.

Kohanski MA, Dwyer DJ, Hayete B, Lawrence CA, Collins JJ.Cell. 2007 Sep 7;130(5):797-810. doi: 10.1016/j.cell.2007.06.049.PMID: 17803904

 

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