Lynch Syndrome Symposium

Agenda and Videos

Monday, March 11, 2024
10am - 6pm

Symposium organizers: Bryson Katona, MD, PhD and E. John Wherry, PhD

Please note that not all sessions will be available to virtual attendees.

10:00am – 10:05am	Welcome and Opening Remarks	E. John Wherry, PhD
10:05am – 10:20am	Overview of Penn’s Lynch syndrome program	Bryson Katona, MD, PhD
10:20am – 10:30am	Opportunities for giving	Tricia Bruning

Clinical Care Symposium - Moderator: Jessica Long, MS, CGC

10:30am – 11:00am	Lynch syndrome genetics and cancer risk	Jessica Long, MS, CGC
11:00am – 11:20am	Colorectal surgery options and considerations in Lynch syndrome	Erica Pettke, MD
11:20am - 11:40am	Immunotherapy for treatment of Lynch syndrome-associated cancers	Parul Agarwal, MD
11:40am-12:00pm	What’s new this year in Lynch syndrome	Derek Mann, MS, CGC

12:00pm-12:40pm	Lunch with the experts (in-person attendees only)
Oncology \| Parul Agarwal, MD and Kim Reiss-Binder, MD Adult Genetics \| Jessica Long, MS, CGC and Derek Mann, MS, CGC Pediatric Genetics \| Sarah Baldino, MS, CGC and Mary Egan Clark, MD, CGC Gynecology \| Emily Ko, MD and Elizabeth Clement, MD Surgery \| Erica Pettke, MD Gastroenterology \| Michael Kochman, MD Nutrition \| Jessica Griffin, RD and Laura Dickens, RD Urology \| Bruce Malkowicz, MD Research \| Michaela Dungan and Daniel Clay Dermatology \| Cerrene Giordano, MD
12:40pm - 1:40pm	Expert panel discussion - Moderator: Bryson Katona, MD, PhD
Gastroenterology \| Michael Kochman, MD Gynecology \| Elizabeth Clement, MD and Emily Ko, MD Genetics \| Jessica Long, MS, CGC Urology \| Bruce Malkowicz, MD Colorectal surgery \| Najjia Mahmoud, MD Oncology \| Kim Reiss-Binder, MD Nutrition \| Jessica Griffin, RD Dermatology \| Cerrene Giordano, MD

1:40pm - 2:40pm

Borrelli Family Keynote talk

Lynch syndrome immunology – implications for cancer risk and prevention

Matthias Kloor, MD

2:40pm - 3:00pm

Break

Research Symposium - Moderator: E. John Wherry, PHD

3:00pm - 3:20pm	Neoantigen-specific memory T cell responses in Lynch Syndrome carriers – (Borrelli Family Lynch syndrome pilot grant recipient)	Alexander Huang, MD
3:20pm - 3:40pm	Beta-hydroxybutyrate supplementation in Lynch syndrome	Bhoomi Madhu, PhD
3:40pm - 4:00pm	Defining the mucosal immune environment in Lynch syndrome	Ken Cadwell, PhD
4:00pm - 4:20pm	Colonic neoplasia detection rate in Lynch syndrome	Daniela Mirda, MD
4:20pm - 4:40pm	Flu vaccine immune responses in Lynch syndrome and BRCA1/2 carriers	Bria Fulmer
4:40pm - 5:00pm	Environment and lifestyle control of colorectal cancer susceptibility	Christoph Thaiss, PhD
5:00pm - 6:00pm	Cocktail Hour (in-person attendees only)